Ruiz-Irastorza G, Khamashta M A
Service and Department of Internal Medicine, Hospital de Cruces, University of the Basque Country, Bizkaia.
Z Rheumatol. 2006 May;65(3):192-4, 196-9. doi: 10.1007/s00393-006-0058-z.
Women with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are subject to several complications during pregnancy, including reactivation of SLE, thrombosis, miscarriage, neonatal lupus, pregnancy-induced hypertension, pulmonary hypertension and drug toxicity. Correct management of these patients requires combined medical-obstetric care, close surveillance of baby's growth and well-being, control of SLE activity and correct thromboprophylaxis. With good care, most pregnancies in women with SLE and APS end successfully.