Gromnica-Ihle E, Ostensen M
Rheumapraxis Berlin-Pankow, Berlin.
Z Rheumatol. 2006 May;65(3):209-12, 214-6. doi: 10.1007/s00393-006-0053-4.
The activity of a rheumatic disease can be influenced by pregnancy and puerperium. Prospective studies have shown an improvement in joint involvement in rheumatoid arthritis in two thirds to three quarters of pregnancies. After birth, an exacerbation is common. In spondylarthropathies there is no relevant change in disease activity. The fetal outcome is not impaired in patients with rheumatoid arthritis and inflammatory spondylarthropathies. Every pregnancy in women with a rheumatic disease should be considered as high-risk, and such pregnancies require close collaboration between rheumatologists and obstetricians.
妊娠和产褥期可影响风湿性疾病的活动。前瞻性研究表明,三分之二至四分之三的类风湿关节炎患者在孕期关节受累情况有所改善。产后病情加重较为常见。在脊柱关节病中,疾病活动度无相关变化。类风湿关节炎和炎性脊柱关节病患者的胎儿结局不受影响。每一例患有风湿性疾病的女性妊娠都应被视为高危妊娠,此类妊娠需要风湿科医生和产科医生密切合作。