Division of Rheumatology, University of California Los Angeles, Veterans Association Greater Los Angeles Health System, Los Angeles, CA, USA.
Curr Rheumatol Rep. 2010 Oct;12(5):355-62. doi: 10.1007/s11926-010-0121-2.
With advancing therapeutic options, achieving a state of remission has become the treatment goal in rheumatoid arthritis. Agreeing on what constitutes remission and what measures should be used to assess disease activity has remained a challenge. Multiple remission criteria have been devised and modified, all with different strengths and limitations. A consensus definition of remission will need to be achieved if we are to be able to evaluate outcomes of clinical trials and establish treatment targets for practice. Remission defined as the complete absence of disease currently may not be a realistic therapeutic goal.
随着治疗选择的不断进步，在类风湿关节炎中达到缓解状态已成为治疗目标。对于什么是缓解以及应该使用哪些措施来评估疾病活动，仍然存在挑战。已经设计并修改了多种缓解标准，它们都具有不同的优缺点。如果我们要能够评估临床试验的结果并为实践确定治疗目标，就需要达成缓解的共识定义。目前，将疾病完全消除定义为缓解可能不是一个现实的治疗目标。
