• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Modulation by acetylcholine of adrenergic transmission in the rabbit ear artery.乙酰胆碱对兔耳动脉肾上腺素能传递的调节作用。
Br J Pharmacol. 1975 May;54(1):49-53. doi: 10.1111/j.1476-5381.1975.tb07408.x.
2
Facilitatory effect of nicotine on adrenergic neuroeffector transmission in the isolated ear artery of the rabbit.尼古丁对家兔离体耳动脉肾上腺素能神经效应器传递的易化作用。
J Pharm Pharmacol. 1980 Feb;32(2):92-6. doi: 10.1111/j.2042-7158.1980.tb12859.x.
3
Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery.拟副交感神经药对兔耳动脉肾上腺素能神经传递的抑制作用。
J Pharmacol Exp Ther. 1973 Feb;184(2):346-56.
4
Modulation of noradrenergic transmission in the rabbit ear artery by dopamine.多巴胺对兔耳动脉去甲肾上腺素能传递的调节作用。
Br J Pharmacol. 1978 Dec;64(4):527-37. doi: 10.1111/j.1476-5381.1978.tb17314.x.
5
The effects of cholinomimetic drugs on responses to sympathetic nerve stimulation and noradrenaline in the rabbit ear artery.拟胆碱药物对兔耳动脉交感神经刺激反应及去甲肾上腺素的影响。
Br J Pharmacol. 1970 Apr;38(4):758-70. doi: 10.1111/j.1476-5381.1970.tb09885.x.
6
Effects of the muscarinic agonist McN-A-343 on the release by sympathetic nerve stimulation of (3H)-noradrenaline from rabbit isolated ear arteries and guinea-pig atria.毒蕈碱激动剂 McN - A - 343 对兔离体耳动脉和豚鼠心房交感神经刺激释放(3H)-去甲肾上腺素的影响。
Br J Pharmacol. 1974 May;51(1):29-34. doi: 10.1111/j.1476-5381.1974.tb09628.x.
7
Effect of acetylcholine on the response of the isolated rabbit ear artery to stimulation of the perivascular sympathetic nerves.乙酰胆碱对离体兔耳动脉对血管周围交感神经刺激反应的影响。
Eur J Pharmacol. 1972 Feb;17(2):227-33. doi: 10.1016/0014-2999(72)90163-x.
8
Vasoconstriction of the isolated rabbit ear artery caused by nicotinic agonists acting on adrenergic neurons.作用于肾上腺素能神经元的烟碱样激动剂引起的离体兔耳动脉血管收缩。
J Pharmacol Exp Ther. 1975 Apr;193(1):128-37.
9
Cerebral blood vessels: effects of exogenous acetylcholine and field stimulation on norepinephrine release.脑血管:外源性乙酰胆碱和场刺激对去甲肾上腺素释放的影响。
J Pharmacol Exp Ther. 1982 Sep;222(3):562-5.
10
Possibilities for a cholinergic action on smooth musculature and on sympathetic axons in brain vessels mediated by muscarinic and nicotinic receptors.由毒蕈碱型和烟碱型受体介导的胆碱能作用于脑血管平滑肌和交感神经轴突的可能性。
J Pharmacol Exp Ther. 1977 Jan;200(1):117-26.

引用本文的文献

1
Parasympathomimetic influence of carbachol on local cerebral blood flow in the rabbit by a direct vasodilator action and an inhibition of the sympathetic-mediated vasoconstriction.卡巴胆碱通过直接血管舒张作用和抑制交感神经介导的血管收缩,对兔局部脑血流量产生拟副交感神经作用。
Br J Pharmacol. 1980 Mar;68(3):449-59. doi: 10.1111/j.1476-5381.1980.tb14558.x.
2
Endotoxin impairs the response of rabbit mesenteric artery to electrical stimulation via a prejunctional mechanism.内毒素通过一种节前机制损害兔肠系膜动脉对电刺激的反应。
Br J Pharmacol. 1992 Nov;107(3):826-32. doi: 10.1111/j.1476-5381.1992.tb14531.x.
3
Presynaptic receptor systems on the noradrenergic neurones of the rabbit pulmonary artery.兔肺动脉去甲肾上腺素能神经元上的突触前受体系统
Naunyn Schmiedebergs Arch Pharmacol. 1977 Feb;296(3):229-47. doi: 10.1007/BF00498689.
4
Presynaptic receptor systems on the noradrenergic neurones of rat brain.
Naunyn Schmiedebergs Arch Pharmacol. 1977 Sep;299(2):123-41. doi: 10.1007/BF00498554.

本文引用的文献

1
Sympathetic postganglionic cholinergic fibres.交感神经节后胆碱能纤维。
Br J Pharmacol Chemother. 1960 Mar;15(1):56-66. doi: 10.1111/j.1476-5381.1960.tb01210.x.
2
The effects of cholinomimetic drugs on responses to sympathetic nerve stimulation and noradrenaline in the rabbit ear artery.拟胆碱药物对兔耳动脉交感神经刺激反应及去甲肾上腺素的影响。
Br J Pharmacol. 1970 Apr;38(4):758-70. doi: 10.1111/j.1476-5381.1970.tb09885.x.
3
Effect of acetylcholine on the response of the isolated rabbit ear artery to stimulation of the perivascular sympathetic nerves.乙酰胆碱对离体兔耳动脉对血管周围交感神经刺激反应的影响。
Eur J Pharmacol. 1972 Feb;17(2):227-33. doi: 10.1016/0014-2999(72)90163-x.
4
Comparison of effects of six cholinomimetic drugs on inhibition of uptake of 3 H-( )-noradrenaline by guinea-pig atria.六种拟胆碱药物对豚鼠心房抑制3H-()-去甲肾上腺素摄取作用的比较。 (注:原文括号处内容缺失)
Br J Pharmacol. 1973 Jan;47(1):179-80. doi: 10.1111/j.1476-5381.1973.tb08172.x.
5
Inhibition of norepinephrine- 3 H release from sympathetic nerve endings in veins by acetylcholine.乙酰胆碱对静脉交感神经末梢去甲肾上腺素-3H释放的抑制作用。
J Pharmacol Exp Ther. 1973 May;185(2):386-94.
6
Venous relaxation caused by acetylcholine acting on the sympathetic nerves.乙酰胆碱作用于交感神经引起的静脉舒张。
Circ Res. 1973 Feb;32(2):259-67. doi: 10.1161/01.res.32.2.259.
7
Effects of acetylcholine on vasoconstriction and release of 3 H-noradrenaline in response to sympathetic nerve stimulation in the isolated artery of the rabbit ear.乙酰胆碱对兔耳离体动脉中交感神经刺激所引起的血管收缩及3H-去甲肾上腺素释放的影响。
Br J Pharmacol. 1972 Nov;46(3):527P-528P.
8
Techniques for studying adrenergic transmitter release in an isolated perfused artery.在离体灌注动脉中研究肾上腺素能递质释放的技术。
Cardiovasc Res. 1973 May;7(3):423-8. doi: 10.1093/cvr/7.3.423.
9
Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery.拟副交感神经药对兔耳动脉肾上腺素能神经传递的抑制作用。
J Pharmacol Exp Ther. 1973 Feb;184(2):346-56.
10
Modification of the evoked release of noradrenaline from the perfused cat spleen by various ions and agents.不同离子和试剂对灌注猫脾脏中去甲肾上腺素诱发释放的影响。
J Physiol. 1972 Mar;221(3):601-15. doi: 10.1113/jphysiol.1972.sp009770.

乙酰胆碱对兔耳动脉肾上腺素能传递的调节作用。

Modulation by acetylcholine of adrenergic transmission in the rabbit ear artery.

作者信息

Allen G S, Glover A B, McCulloch M W, Rand M J, Story D F

出版信息

Br J Pharmacol. 1975 May;54(1):49-53. doi: 10.1111/j.1476-5381.1975.tb07408.x.

DOI:10.1111/j.1476-5381.1975.tb07408.x
PMID:166718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1666394/
Abstract
  1. Low concentrations of acetylcholine (4 times 10(-11) and 1 times 10(-10) M) increase the vasoconstrictor response of the isolated ear artery of the rabbit to stimulation of the periarterial sympathetic nerves. Higher concentrations (4 times 10(-8) M and greater) decrease the response. 2. Low concentrations of acetylcholine (1 times 10(-11) and 1 times 10(-10) M) increase the stimulation-induced efflux of radioactivity from artery segments previously incubated with [3H]-noradrenaline. Higher ocncentrations (3 times 10(-8) M and greater) decrease the efflux. 3. Neither atropine nor hexamethonium affects the facilitatory action of low concentrations of acetylcholine on adrenergic transmission in the rabbit ear artery. 4. Atropine antagonizes the inhibitory effect of higher concentrations of acetylcholine on adrenergic transmission.
摘要
  1. 低浓度的乙酰胆碱(4×10⁻¹¹和1×10⁻¹⁰M)可增强兔离体耳动脉对动脉周围交感神经刺激的血管收缩反应。较高浓度(4×10⁻⁸M及更高)则降低该反应。2. 低浓度的乙酰胆碱(1×10⁻¹¹和1×10⁻¹⁰M)可增加先前用[³H] - 去甲肾上腺素孵育的动脉段中刺激诱导的放射性流出。较高浓度(3×10⁻⁸M及更高)则降低流出量。3. 阿托品和六甲铵均不影响低浓度乙酰胆碱对兔耳动脉肾上腺素能传递的促进作用。4. 阿托品可拮抗较高浓度乙酰胆碱对肾上腺素能传递的抑制作用。