六种拟胆碱药物对豚鼠心房抑制3H-（）-去甲肾上腺素摄取作用的比较。 （注：原文括号处内容缺失）
Comparison of effects of six cholinomimetic drugs on inhibition of uptake of 3 H-( )-noradrenaline by guinea-pig atria.
作者信息
Allen G S, Rand M J, Story D F
出版信息
Br J Pharmacol. 1973 Jan;47(1):179-80. doi: 10.1111/j.1476-5381.1973.tb08172.x.
Abstract
The effects of N,N-dimethyl-N'-phenyl-piperazinium (DMPP), 4-(m-chlorophenyl-carbamoyloxy) - 2 - butynyltrimethylammonium chloride (McN-A-343), pilocarpine, acetylcholine, methacholi-ne and nicotine in inhibiting the uptake of (3)H-(+/-)-noradrenaline by guinea-pig atria were compared. In concentrations of 1 x 10(-4)M, the percentage inhibitions were as follows: DMPP, 89.1%; McN-A-343, 78.7%; pilocarpine 43.5%; acetylcholine, 35.7%; methacholine, 32.9%; nicotine, 21.6%.
摘要
比较了N，N-二甲基-N'-苯基哌嗪鎓（DMPP）、4-（间氯苯基氨甲酰氧基）-2-丁炔基三甲基氯化铵（McN-A-343）、毛果芸香碱、乙酰胆碱、醋甲胆碱和尼古丁对豚鼠心房摄取（3）H-（+/-）-去甲肾上腺素的抑制作用。在1×10（-4）M的浓度下，抑制百分比分别如下：DMPP为89.1%；McN-A-343为78.7%；毛果芸香碱为43.5%；乙酰胆碱为35.7%；醋甲胆碱为32.9%；尼古丁为21.6%。
相似文献
1
Comparison of effects of six cholinomimetic drugs on inhibition of uptake of 3 H-( )-noradrenaline by guinea-pig atria.六种拟胆碱药物对豚鼠心房抑制3H-（）-去甲肾上腺素摄取作用的比较。 （注：原文括号处内容缺失）
Br J Pharmacol. 1973 Jan;47(1):179-80. doi: 10.1111/j.1476-5381.1973.tb08172.x.
2
Effects of McN-A-343 and DMPP on the uptake and release of 3 H-noradrenaline by guinea-pig atria.McN - A - 343和二甲基苯基哌嗪对豚鼠心房摄取和释放3H - 去甲肾上腺素的影响。
Br J Pharmacol. 1972 Jul;45(3):480-9. doi: 10.1111/j.1476-5381.1972.tb08105.x.
3
Effects of several muscarinic agonists on cardiac performance and the release of noradrenaline from sympathetic nerves of the perfused rabbit heart.几种毒蕈碱激动剂对灌注兔心脏的心脏功能及交感神经去甲肾上腺素释放的影响。
Br J Pharmacol. 1972 Aug;45(4):616-29. doi: 10.1111/j.1476-5381.1972.tb08119.x.
4
Atropine-resistant effects of the muscarinic agonists McN-A-343 and AHR 602 on cardiac performance and the release of noradrenaline from sympathetic nerves of the perfused rabbit heart.毒蕈碱激动剂 McN - A - 343 和 AHR 602 对灌注兔心脏的心脏功能及交感神经去甲肾上腺素释放的抗阿托品作用。
Br J Pharmacol. 1974 Apr;50(4):531-41. doi: 10.1111/j.1476-5381.1974.tb08586.x.
5
Effect of muscarinic agonists on the release of (3H)noradrenaline from the guinea-pig perfused heart.毒蕈碱激动剂对豚鼠离体灌流心脏释放（3H）去甲肾上腺素的影响。
J Pharm Pharmacol. 1974 Jun;26(6):458-60. doi: 10.1111/j.2042-7158.1974.tb09315.x.
6
Pharmacological studies on the hypogastric ganglion of the rat and guinea-pig.大鼠和豚鼠腹下神经节的药理学研究。
Br J Pharmacol. 1972 Mar;44(3):492-509. doi: 10.1111/j.1476-5381.1972.tb07286.x.
7
Inhibition of adrenergic neurotransmission by parasympathomimetics in the rabbit ear artery.拟副交感神经药对兔耳动脉肾上腺素能神经传递的抑制作用。
J Pharmacol Exp Ther. 1973 Feb;184(2):346-56.
8
Effects of the muscarinic agonist McN-A-343 on the release by sympathetic nerve stimulation of (3H)-noradrenaline from rabbit isolated ear arteries and guinea-pig atria.毒蕈碱激动剂 McN - A - 343 对兔离体耳动脉和豚鼠心房交感神经刺激释放（3H）-去甲肾上腺素的影响。
Br J Pharmacol. 1974 May;51(1):29-34. doi: 10.1111/j.1476-5381.1974.tb09628.x.
9
The actions of some cholinomimetic drugs on the isolated taenia of the guinea-pig caecum.某些拟胆碱药物对豚鼠盲肠离体绦虫的作用。
Br J Pharmacol. 1969 May;36(1):53-69. doi: 10.1111/j.1476-5381.1969.tb08303.x.
10
The pharmacology fo gross behavioural effects of cholinomimetic substances injected into the cerebral ventricles of unanaesthetized cats: evidence for central muscarinic mediation.向未麻醉猫的脑室注射拟胆碱物质产生总体行为效应的药理学：中枢毒蕈碱介导的证据
Neuropharmacology. 1974 Dec;13(12):1163-9. doi: 10.1016/0028-3908(74)90066-5.
引用本文的文献
1
Interaction between the inhibitory action of acetylcholine and the alpha-adrenoceptor autoinhibitory feedback system on release of [3H]-noradrenaline from rat atria and rabbit ear artery.乙酰胆碱的抑制作用与α-肾上腺素能受体自身抑制反馈系统对大鼠心房和兔耳动脉中[3H]-去甲肾上腺素释放的相互作用。
Br J Pharmacol. 1985 Mar;84(3):697-705. doi: 10.1111/j.1476-5381.1985.tb16152.x.
2
Modulation by acetylcholine of adrenergic transmission in the rabbit ear artery.乙酰胆碱对兔耳动脉肾上腺素能传递的调节作用。
Br J Pharmacol. 1975 May;54(1):49-53. doi: 10.1111/j.1476-5381.1975.tb07408.x.
本文引用的文献
1
Modification by acetylcholine of the response of rat mesenteric arteries to sympathetic stimulation.乙酰胆碱对大鼠肠系膜动脉交感神经刺激反应的调节作用。
Circ Res. 1969 Jul;25(1):1-9. doi: 10.1161/01.res.25.1.1.
2
A muscarinic mechanism inhibiting the release of noradrenaline from peripheral adrenergic nerve fibres by nicotinic agents.一种毒蕈碱机制，通过烟碱样物质抑制外周肾上腺素能神经纤维释放去甲肾上腺素。
Br J Pharmacol Chemother. 1968 Feb;32(2):280-94. doi: 10.1111/j.1476-5381.1968.tb00972.x.
3
The effects of cholinomimetic drugs on responses to sympathetic nerve stimulation and noradrenaline in the rabbit ear artery.拟胆碱药物对兔耳动脉交感神经刺激反应及去甲肾上腺素的影响。
Br J Pharmacol. 1970 Apr;38(4):758-70. doi: 10.1111/j.1476-5381.1970.tb09885.x.
4
Effects of the muscarinic agonist McN-A-343 on responses to sympathetic nerve stimulation in the rabbit ear artery.毒蕈碱激动剂 McN-A-343 对兔耳动脉交感神经刺激反应的影响。
Br J Pharmacol. 1971 Nov;43(3):536-42. doi: 10.1111/j.1476-5381.1971.tb07183.x.
5
Effects of McN-A-343 and DMPP on the uptake and release of 3 H-noradrenaline by guinea-pig atria.McN - A - 343和二甲基苯基哌嗪对豚鼠心房摄取和释放3H - 去甲肾上腺素的影响。
Br J Pharmacol. 1972 Jul;45(3):480-9. doi: 10.1111/j.1476-5381.1972.tb08105.x.
6
Modification of the vascular response to isoprenaline by cholinomimetic drugs.拟胆碱药对血管对异丙肾上腺素反应的影响
Br J Pharmacol. 1971 Jun;42(2):254-62. doi: 10.1111/j.1476-5381.1971.tb07106.x.
Zotero 插件