Itakura C, Carlson H C
Can J Comp Med. 1975 Jul;39(3):299-304.
The spleen, liver, bone marrow and intestines of two turkeys in which hemorrhagic enteritis of turkeys was experimentally reproduced were examined electron-microscopically. Intranuclear inclusion bodies as described in a previous report were found in all the tissues examined. These occupied most of the area in affected nuclei and were composed of viral particles with morphological characteristics of an adenovirus. The cells with the inclusions were divided into two types of cells, immature and reticular cells. There was some variety in the stage of differentiation of the former cells. As the viral particles developed the cells degenerated and disintegrated. A few particles had been released into the cytoplasm of the degenerated cells but no particles were present in intercellular spaces.
对两只通过实验诱发火鸡出血性肠炎的火鸡的脾脏、肝脏、骨髓和肠道进行了电子显微镜检查。在所有检查的组织中均发现了如先前报告中所述的核内包涵体。这些包涵体占据了受影响细胞核的大部分区域，由具有腺病毒形态特征的病毒颗粒组成。含有包涵体的细胞分为未成熟细胞和网状细胞两种类型。前一种细胞的分化阶段存在一定差异。随着病毒颗粒的发育，细胞发生退化和崩解。少数颗粒已释放到退化细胞的细胞质中，但细胞间隙中没有颗粒。
