Kulagina V P, Trubetskoĭ A V, Udel'nov M G
Biull Eksp Biol Med. 1976 Aug;82(8):923-6.
It was shown that the constrictor responses to the electrostimulation of the isolated vessel segments were replaced by dilatation when the drugs were contained in the lactic acid solution. The capacity to constrictor effects was not lost completely, but these effects appeared in repsonse to the intensive stimulation. Changes in the character of these reactions to the electrostimulation were connected with the changes in the pH of the solution, as well as with the specific action of lactic acid.
结果表明,当药物存在于乳酸溶液中时,对离体血管段电刺激的收缩反应被扩张反应所取代。收缩效应的能力并未完全丧失,但这些效应是在强烈刺激下出现的。对电刺激的这些反应特征的变化与溶液pH值的变化以及乳酸的特定作用有关。