[钙在利血平作用下血管反应性变化机制中的作用]
[Role of calcium in the mechanism of the change in vascular reactivity under the action of reserpine].
作者信息
Kulagina V P
出版信息
Biull Eksp Biol Med. 1979 Jul;88(7):45-8.
PMID:465718
Abstract
Reserpine induces an appreciable reduction of the calcium content in the segments of the distal aorta and rabbit femoral arteries incubated in a saline. These changes develop simultaneously to those in the reaction pattern of the vascular segment to direct electric stimulation (decline of constrictor responses and their subsequent replacement by relaxation). It is postulated that the decreased calcium content in the vascular wall may be one of the causes of altered vascular reactivity.
摘要
利血平可使在盐溶液中孵育的兔主动脉远端节段和股动脉的钙含量显著降低。这些变化与血管节段对直接电刺激的反应模式变化同时出现（收缩反应减弱，随后被舒张反应取代）。据推测，血管壁中钙含量的降低可能是血管反应性改变的原因之一。
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