Yoritaka Asako, Hishima Tsunekazu, Akagi Kumiko, Kishida Shuji
Department of Neurology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
J Dermatol. 2006 Apr;33(4):265-7. doi: 10.1111/j.1346-8138.2006.00064.x.
The pathogenesis of idiopathic-acquired hypohidrosis remains unknown, and no specific causes have yet been established. We report a 34-year-old man with acquired idiopathic hypohidrosis successfully treated with prednisolone. The patient noticed heat intolerance and hypohidrosis of the pectoral and back during the summer. No systemic disease or neurological findings were identified. Eccrine sweat glands displayed infiltration by inflammatory cells, with immunoglobulin G and C3 deposition in the basement membrane. Steroid therapy improved the hypohidrosis. An immunological pathogenesis could be a major factor in idiopathic-acquired hypohidrosis.
