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[宫颈癌中人乳头瘤病毒(HPV)的型别分布]

[Type distribution of human papilloma virus (HPV) in cervical cancer].

作者信息

Guo Y

出版信息

Zhonghua Yi Xue Za Zhi. 1991 Jun;71(6):321-2, 24.

PMID:1667495
Abstract

For analysis of the relationship between HPV type and the progress of cervical cancer, we investigated the distribution of HPV genome type in 171 cases of papilloma, cervical neoplasm early cancer and invasive cancer. The results showed that Chinese Human Papilloma Virus type 16 (CHPV16) and Chinese Human Papilloma Virus non-classified type 1 (CHPVX1) have positive rates 11.5%, 4.8%, 50.0% and 48.8%, respectively. While HPV11/HPV6 decreased with developing of cervical neoplasia. Their positive rate was 76.9%, 26.8%, 10.0% and 2.4%, respectively. There was significant difference (P less than 0.01) in X2 test for trend. It was indicated that there is a strong correlation between the CHPV16/CHPVX1 and the developing of cervical cancer.

摘要

为分析人乳头瘤病毒(HPV)类型与宫颈癌进展之间的关系,我们调查了171例乳头状瘤、宫颈肿瘤早期癌症和浸润性癌症中HPV基因组类型的分布。结果显示,中国16型人乳头瘤病毒(CHPV16)和中国未分类1型人乳头瘤病毒(CHPVX1)的阳性率分别为11.5%、4.8%、50.0%和48.8%。而HPV11/HPV6随着宫颈肿瘤的发展而降低,其阳性率分别为76.9%、26.8%、10.0%和2.4%。趋势性X2检验存在显著差异(P小于0.01)。表明CHPV16/CHPVX1与宫颈癌的发展之间存在强相关性。

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