Edlund Mark J, Harris Katherine M
Department of Psychiatry of the Central Arkansas Veterans Health System, North Little Rock, Arkansas 72114, USA.
Psychiatr Serv. 2006 May;57(5):692-9. doi: 10.1176/ps.2006.57.5.692.
No consensus exists on the use of psychiatric medication among patients with co-occurring mental health and alcohol disorders. The authors investigated patterns of use of psychiatric medication and perceived effectiveness of mental health treatment among users of mental health care with and without alcohol dependence.
Data were obtained from the 2001 to 2003 National Survey on Drug Use and Health. The sample consisted of respondents who reported receiving mental health treatment in the past year (N=11,872). Rates of psychiatric medication use were compared between mental health care patients who were alcohol dependent and those who were not. Patient-reported effectiveness of mental health treatment was examined among alcohol-dependent and non-alcohol dependent patients who did and did not receive psychiatric medication.
No statistically significant differences in rates of use of psychiatric medication were found between those with and without alcohol dependence (76.2 percent and 75.9 percent, respectively). Among alcohol-dependent patients, those who received psychiatric medication were significantly more likely than those who did not receive such medication to report that treatment helped a lot or a great deal (OR=2.87, 95 percent CI=1.57 to 2.56, p<.001). Among those who received psychiatric medication, no statistically significant differences were found between alcohol-dependent and nondependent respondents in patients' ratings of treatment effectiveness.
Most alcohol-dependent individuals in mental health treatment received psychiatric medication, despite the lack of guideline support in this area. A large majority of those with alcohol dependence who received psychiatric medication reported that mental health treatment was effective.
对于同时患有精神健康和酒精障碍的患者使用精神科药物，目前尚无共识。作者调查了有酒精依赖和无酒精依赖的精神卫生保健使用者的精神科药物使用模式以及对心理健康治疗效果的认知。
数据来自2001年至2003年的全国药物使用和健康调查。样本包括报告在过去一年接受过心理健康治疗的受访者（N = 11,872）。比较了酒精依赖的精神卫生保健患者和非酒精依赖患者的精神科药物使用率。在接受和未接受精神科药物治疗的酒精依赖和非酒精依赖患者中，检查了患者报告的心理健康治疗效果。
有酒精依赖和无酒精依赖的患者在精神科药物使用率上没有统计学上的显著差异（分别为76.2%和75.9%）。在酒精依赖患者中，接受精神科药物治疗的患者比未接受此类药物治疗的患者更有可能报告治疗有很大帮助（OR = 2.87，95%CI = 1.57至2.56，p <.001）。在接受精神科药物治疗的患者中，酒精依赖和非依赖受访者在治疗效果评分上没有统计学上的显著差异。
尽管该领域缺乏指南支持，但大多数接受心理健康治疗的酒精依赖个体接受了精神科药物治疗。绝大多数接受精神科药物治疗的酒精依赖患者报告心理健康治疗有效。
