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美国《精神疾病诊断与统计手册》第四版中酒精滥用与酒精依赖的患病率、相关因素、残疾情况及共病情况:酒精及相关疾病全国流行病学调查结果

Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

作者信息

Hasin Deborah S, Stinson Frederick S, Ogburn Elizabeth, Grant Bridget F

机构信息

Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, New York, USA.

出版信息

Arch Gen Psychiatry. 2007 Jul;64(7):830-42. doi: 10.1001/archpsyc.64.7.830.

Abstract

CONTEXT

Epidemiologic information is important to inform etiological research and service delivery planning. However, current information on the epidemiology of alcohol use disorders in the United States is lacking.

OBJECTIVES

To present nationally representative findings on the prevalence, correlates, psychiatric comorbidity, and treatment of DSM-IV alcohol abuse and dependence.

DESIGN, SETTING, AND PARTICIPANTS: Face-to-face interviews with a representative US adult sample (N = 43 093).

MAIN OUTCOME MEASURES

Lifetime and 12-month DSM-IV alcohol abuse and dependence.

RESULTS

Prevalence of lifetime and 12-month alcohol abuse was 17.8% and 4.7%; prevalence of lifetime and 12-month alcohol dependence was 12.5% and 3.8%. Alcohol dependence was significantly more prevalent among men, whites, Native Americans, younger and unmarried adults, and those with lower incomes. Current alcohol abuse was more prevalent among men, whites, and younger and unmarried individuals while lifetime rates were highest among middle-aged Americans. Significant disability was particularly associated with alcohol dependence. Only 24.1% of those with alcohol dependence were ever treated, slightly less than the treatment rate found 10 years earlier. Strong associations between other substance use disorders and alcohol use disorders (odds ratios, 2.0-18.7) were lower but remained strong and significant (odds ratios, 1.8-7.5) when controlling for other comorbidity. Significant associations between mood, anxiety, and personality disorders and alcohol dependence (odds ratios, 2.1-4.8) were reduced in number and magnitude (odds ratios, 1.5-2.0) when controlling for other comorbidity.

CONCLUSIONS

Alcohol abuse and dependence remain highly prevalent and disabling. Comorbidity of alcohol dependence with other substance disorders appears due in part to unique factors underlying etiology for each pair of disorders studied while comorbidity of alcohol dependence with mood, anxiety, and personality disorders appears more attributable to factors shared among these other disorders. Persistent low treatment rates given the availability of effective treatments indicate the need for vigorous education efforts for the public and professionals.

摘要

背景

流行病学信息对于病因学研究和服务提供规划至关重要。然而,目前美国缺乏关于酒精使用障碍流行病学的信息。

目的

呈现关于《精神疾病诊断与统计手册》第四版(DSM-IV)中酒精滥用和酒精依赖的患病率、相关因素、精神共病情况及治疗的全国代表性研究结果。

设计、研究地点和参与者:对具有代表性的美国成年样本(N = 43093)进行面对面访谈。

主要观察指标

终生及过去12个月内的DSM-IV酒精滥用和酒精依赖情况。

结果

终生酒精滥用患病率为17.8%,过去12个月酒精滥用患病率为4.7%;终生酒精依赖患病率为12.5%,过去12个月酒精依赖患病率为3.8%。酒精依赖在男性、白人、美国原住民、年轻及未婚成年人以及低收入者中更为普遍。当前酒精滥用在男性、白人、年轻及未婚个体中更为普遍,而终生患病率在美国中年人群中最高。严重残疾尤其与酒精依赖相关。仅有24.1%的酒精依赖者曾接受过治疗,略低于10年前的治疗率。在控制其他共病情况时,其他物质使用障碍与酒精使用障碍之间的强关联(优势比,2.0 - 18.7)虽有所降低,但仍很强且具有统计学意义(优势比,1.8 - 7.5)。在控制其他共病情况时,情绪、焦虑和人格障碍与酒精依赖之间的显著关联(优势比,2.

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