He Yongheng, Tang Zhilie, Chen Zhanxu, Wan Wei, Li Jianghua
School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, People's Republic of China.
Phys Med Biol. 2006 May 21;51(10):2671-80. doi: 10.1088/0031-9155/51/10/019. Epub 2006 May 4.
A novel photoacoustic (PA) tomographic method, which is based on a time-resolved technique and an acoustic lens imaging system, is presented in this paper. A YAG laser operating at 532 nm with a 7 ns pulse width and 10 mJ optical pulse is employed as the excitation source to irradiate the tissue. PA signals generated from the tissue are imaged onto a multi-element linear array transducer with an acoustic lens. A 64 electronic switch is efficiently used for changing the parallel PA signals into a series. The proposed method directly provides PA images without any complex reconstruction algorithms. With the time-resolved technique, tomographic imaging can be achieved successfully. The results show that the images agree well with the original samples.
本文提出了一种基于时间分辨技术和声学透镜成像系统的新型光声（PA）层析成像方法。采用波长为532nm、脉冲宽度为7ns、光脉冲能量为10mJ的YAG激光器作为激发源照射组织。组织产生的光声信号通过声学透镜成像到多元线性阵列换能器上。一个64路电子开关有效地用于将并行光声信号转换为串行信号。该方法无需任何复杂的重建算法即可直接提供光声图像。利用时间分辨技术，可以成功实现层析成像。结果表明，图像与原始样本吻合良好。
