[α-甲基多巴对两种近交系小鼠睡眠和迷宫学习的不同作用]
[Different action of alpha-methyl-DOPA on sleep and labyrinth learning in 2 inbred strains of mice].
作者信息
Kitahama K, Valatx J L, Jouvet M
出版信息
C R Acad Hebd Seances Acad Sci D. 1975 Jan 27;280(4):471-4.
PMID:166767
Abstract
In two inbred mice strains C 57 BR and C 57 BL/6 presenting the same type of sleep, but a different capacity of learning, Alpha-Methyl-Dopa (100 mg/kg) injected after every session, suppresses paradoxical sleep completely for 9 to 11 h. Maze-learning performance is retarded in C 57 BR mice, but facilitated in C 57 BL/6.
摘要
在两种具有相同睡眠类型但学习能力不同的近交系小鼠C 57 BR和C 57 BL/6中，每次训练后注射α-甲基多巴（100毫克/千克）可使异相睡眠完全被抑制9至11小时。在C 57 BR小鼠中，迷宫学习能力受到抑制，但在C 57 BL/6小鼠中则得到促进。
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