Higashino K, Kudo S, Yamamura Y, Honda T, Sakurai J
Clin Chim Acta. 1975 May 1;60(3):267-72. doi: 10.1016/0009-8981(75)90066-2.
The electrophoretically faster migrating alkaline phosphatase isozyme in FL cells derived from the human amniotic membrane was similar in some of the enzymatic and immunochemical properties to the variant alkaline phosphatase which occurs in serum and cancerous tissue of some patients with hepatocellular carcinoma. These facts suggest that the hepatoma-associated alkaline phosphatase may be the resurgence of the isozyme originally present in the amniotic membrane.
源自人羊膜的FL细胞中电泳迁移速度较快的碱性磷酸酶同工酶，在某些酶学和免疫化学特性上，与一些肝细胞癌患者血清和癌组织中出现的变异碱性磷酸酶相似。这些事实表明，肝癌相关碱性磷酸酶可能是羊膜中原本存在的同工酶的重现。
