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[一种焦磷酸盐牙膏对牙石形成的抑制作用]

[Inhibiting effect of a pyrophosphate-dentifrice on calculus formation].

作者信息

Kurbad A, Gängler P, Hoffmann T, Kirchner T, Weinert W

机构信息

Sektion Stomatologie an der Medizinischen Akademie Erfurt.

出版信息

Dtsch Zahnarztl Z. 1991 Apr;46(4):277-80.

PMID:1667753
Abstract

Anticalculus dentifrices containing pyrophosphate salts have been shown to reduce calculus formation. The purpose of this double-blind, cross-over study was to compare the effects of a pyrophosphate dentifrice with a placebo on supragingival calculus formation in highly calculus-prone subjects. 60 volunteers completed a compliance period during which meticulous full-mouth scaling was performed. Subjects were randomly assigned either to placebo (F-Antibelag Gel) or to the test group (F-Antibelag Gel + K4P2O7/Na4P2O7). Participants were told to brush twice daily with their assigned dentifrice, use only the brushes provided and to abstain from any other oral hygiene procedures. After a three month period a second full-mouth scaling was performed, and according to the cross-over design of this study the participants used the alternative placebo or, respectively, dentifrice for another three months. Baseline scores and control scores after 1, 2 and 3 months were obtained using the Volpe-Manhold-Index and the Marginal-Line-Calculus-Index. A micromorphological SEM Calculus Index was introduced using replicas from interdental areas of mandibular incisors (score 0-3). Both test groups showed significantly less accumulation of supragingival calculus of 25.5% (VMI) and 19.5% (MLCI) and significantly less SEM detectable calculus (24%) with the pyrophosphate dentifrice than with the placebo. It is concluded that the test dentifrice inhibits the formation of calculus.

摘要

含有焦磷酸盐的防牙石牙膏已被证明可减少牙石形成。这项双盲交叉研究的目的是比较一种含焦磷酸盐的牙膏与一种安慰剂对牙石形成倾向高的受试者龈上牙石形成的影响。60名志愿者完成了一个依从期,在此期间进行了细致的全口洁治。受试者被随机分为安慰剂组(F-Antibelag凝胶)或试验组(F-Antibelag凝胶+K4P2O7/Na4P2O7)。参与者被告知每天用分配的牙膏刷牙两次,仅使用提供的牙刷,并且避免进行任何其他口腔卫生程序。三个月后进行了第二次全口洁治,根据本研究的交叉设计,参与者再使用另一种安慰剂或相应的牙膏三个月。使用Volpe-Manhold指数和边缘线牙石指数获得基线分数以及1、2和3个月后的对照分数。使用下颌切牙牙间隙区域的复制品引入了一种微观形态学扫描电镜牙石指数(分数0 - 3)。与安慰剂相比,两个试验组使用含焦磷酸盐牙膏时龈上牙石的累积量均显著减少,分别减少了25.5%(VMI)和19.5%(MLCI),并且扫描电镜可检测到的牙石显著减少(24%)。得出的结论是,试验牙膏可抑制牙石的形成。

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