Duff Michael, Dusenbery Kathryn E, Rodriguez Fausto J
University of Minnesota Department of Therapeutic Radiology, MMC 494, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Gynecol Oncol. 2006 Sep;102(3):593-5. doi: 10.1016/j.ygyno.2006.03.031. Epub 2006 May 4.
The incidence of paraneoplastic syndromes varies with tumor histology. Uterine sarcomas rarely cause paraneoplastic syndromes. Furthermore, paraneoplastic encephalomyelitis has never been reported to accompany a uterine leiomyosarcoma.
A 44-year-old female developed an ANNA-1 paraneoplastic encephalomyelitis after a diagnosis of a uterine leiomyosarcoma.
Paraneoplastic encephalomyelitis usually causes progressive neurologic decline. Treatment rarely alters this course.
副肿瘤综合征的发病率因肿瘤组织学类型而异。子宫肉瘤很少引起副肿瘤综合征。此外,从未有过副肿瘤性脑脊髓炎伴发子宫平滑肌肉瘤的报道。
一名44岁女性在诊断为子宫平滑肌肉瘤后发生了抗神经元核抗体1型(ANNA-1)副肿瘤性脑脊髓炎。
副肿瘤性脑脊髓炎通常导致进行性神经功能衰退。治疗很少能改变这一病程。