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副肿瘤性脑脊髓炎:一例病例报告及文献综述

Paraneoplastic encephalomyelitis: a case report and review of the literature.

作者信息

Duff Michael, Dusenbery Kathryn E, Rodriguez Fausto J

机构信息

University of Minnesota Department of Therapeutic Radiology, MMC 494, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

出版信息

Gynecol Oncol. 2006 Sep;102(3):593-5. doi: 10.1016/j.ygyno.2006.03.031. Epub 2006 May 4.

DOI:10.1016/j.ygyno.2006.03.031
PMID:16677693
Abstract

BACKGROUND

The incidence of paraneoplastic syndromes varies with tumor histology. Uterine sarcomas rarely cause paraneoplastic syndromes. Furthermore, paraneoplastic encephalomyelitis has never been reported to accompany a uterine leiomyosarcoma.

CASE

A 44-year-old female developed an ANNA-1 paraneoplastic encephalomyelitis after a diagnosis of a uterine leiomyosarcoma.

CONCLUSION

Paraneoplastic encephalomyelitis usually causes progressive neurologic decline. Treatment rarely alters this course.

摘要

背景

副肿瘤综合征的发病率因肿瘤组织学类型而异。子宫肉瘤很少引起副肿瘤综合征。此外,从未有过副肿瘤性脑脊髓炎伴发子宫平滑肌肉瘤的报道。

病例

一名44岁女性在诊断为子宫平滑肌肉瘤后发生了抗神经元核抗体1型(ANNA-1)副肿瘤性脑脊髓炎。

结论

副肿瘤性脑脊髓炎通常导致进行性神经功能衰退。治疗很少能改变这一病程。

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