Bancillon A, Leblanc T, Baruchel A, Schaison G, Leverger G, Mallarmey D, Teuliere L
Department of Pediatric Hematology, Hôpital Saint-Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1991;33(6):555-6.
Chickenpox could be a severe disease in immunocompromised patients. Live attenuated vaccine is now available. We conducted a trial in 37 leukemic children with OKA varicella vaccine. Full immunization was observed in all 20 seronegative patients. Few side effects and no generalized vaccinal infection were observed. Further studies are warranted to assess the benefit of vaccination in leukemic patients considering the effectiveness of Varicella Zoster Immuno-Globulins and Aciclovir.
水痘在免疫功能低下的患者中可能是一种严重疾病。目前已有减毒活疫苗。我们用OKA水痘疫苗对37名白血病儿童进行了一项试验。所有20名血清阴性患者均实现了完全免疫。观察到很少有副作用，且未出现全身性疫苗感染。考虑到水痘带状疱疹免疫球蛋白和阿昔洛韦的有效性，有必要进一步开展研究以评估疫苗接种对白血病患者的益处。
