Robert M, Sunitha R, Thulaseedharan N K
Department of Neurology, Medical College Hospital, Trivandrum, Kerala, India.
Neurol India. 2006 Mar;54(1):75-7. doi: 10.4103/0028-3886.24713.
Neuropsychiatric systemic lupus erythematosus (NPSLE) has varied manifestations.
To study the pattern of neuropsychiatric (NP) involvement in systemic lupus erythematosus (SLE).
Hospital based cross sectional and retrospective study.
Patients admitted with a diagnosis of SLE, during a period of 16 months, were evaluated and any NP syndrome present classified as per the American College of Rheumatology (ACR) nomenclature.
SPSS software Version 10 was used for descriptive analysis and correlative study.
Out of 50 patients with SLE, all the patients with NPSLE [39 (78%)] were females, mean age 25.66 years (range: 11-44). The commonest manifestation was headache [20 (55.6%)]. Seizures were seen in 8 (20.51%) and psychosis in 6 (16.2%). Fine distal tremor was seen in 8 (20.51%) of patients.
Headache is a frequent NP syndrome. Fine distal tremor is a syndrome not included in ACR classification but seen is 20% of our patients with NPSLE.
神经精神性系统性红斑狼疮（NPSLE）有多种表现形式。
研究系统性红斑狼疮（SLE）患者神经精神（NP）受累情况。
基于医院的横断面回顾性研究。
对16个月期间确诊为SLE的住院患者进行评估，并根据美国风湿病学会（ACR）命名法对出现的任何NP综合征进行分类。
使用SPSS软件版本10进行描述性分析和相关性研究。
50例SLE患者中，所有NPSLE患者[39例（78%）]均为女性，平均年龄25.66岁（范围：11 - 44岁）。最常见的表现是头痛[20例（55.6%）]。8例（20.51%）出现癫痫发作，6例（16.2%）出现精神病症状。8例（20.51%）患者出现精细的远端震颤。
头痛是一种常见的NP综合征。精细的远端震颤是ACR分类中未包括的综合征，但在我们20%的NPSLE患者中可见。
