Yuki Masashi, Sugimoto Noriko, Takahashi Kuniaki, Otsuka Hiromi, Nishii Naohito, Suzuki Kiyomi, Yamagami Tetsushi, Ito Hiroshi
Yuki Animal Hospital, Nagoya, Aichi, Japan.
J Vet Med Sci. 2006 Apr;68(4):397-9. doi: 10.1292/jvms.68.397.
A 9-year-old female Pug was presented to us with chronic diarrhea. Hematologic findings indicated severe hypoproteinemia and hypoalbuminemia, and endoscopy revealed severe edema of the duodenal mucosa. Based on these results and on additional histopathological findings, we made a diagnosis of protein-losing enteropathy caused by lymphocytic-plasmacytic enteritis with lymphangiectasia. The dog was initially treated with prednisolone and cyclosporine. This treatment regimen was not effective. However, when methotrexate was substituted for cyclosporine, progress was obtained and the diagnosis was confirmed.
一只9岁雌性哈巴狗因慢性腹泻前来我院就诊。血液学检查结果显示严重低蛋白血症和低白蛋白血症，内镜检查发现十二指肠黏膜严重水肿。基于这些结果以及其他组织病理学检查结果，我们诊断该犬患有淋巴细胞-浆细胞性肠炎伴淋巴管扩张引起的蛋白丢失性肠病。这只狗最初接受泼尼松龙和环孢素治疗。该治疗方案无效。然而，当用甲氨蝶呤替代环孢素后，病情有了进展并确诊。
