Ma D, Gu M J
Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical University, Wuhan.
J Tongji Med Univ. 1991;11(4):235-9. doi: 10.1007/BF02888158.
Tumor-infiltrating lymphocytes (TIL) in histological sections from 94 patients with ovarian malignancies were quantitated for their relation to the prognosis of the patients. It was found that the degree of lymphocyte infiltration directly affected the patients' survival rate and also related to clinical staging of the patients, as well as grading and histologic typing of the tumor. T lymphocytes characterized by alpha-naphthyl acetate (ANAE) staining were the major cells in the stroma of ovarian malignancies. Ultrastructural study of TIL and cancer cells suggested that tumor cell degeneration is related to the effect of TIL.
对94例卵巢恶性肿瘤患者组织切片中的肿瘤浸润淋巴细胞（TIL）进行定量分析，以研究其与患者预后的关系。发现淋巴细胞浸润程度直接影响患者生存率，且与患者的临床分期、肿瘤分级及组织学类型有关。以α-萘乙酸酯（ANAE）染色为特征的T淋巴细胞是卵巢恶性肿瘤间质中的主要细胞。TIL与癌细胞的超微结构研究表明，肿瘤细胞退变与TIL的作用有关。
