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[The research of the pathogen responsible for Pleurocybella porrigens related encephalopathy: investigation of 3-nitropropionic acid hypothesis].

作者信息

Obara Koji, Muto Hajime, Itoh Hideaki, Satoh Shigeru, Gonmori Kunio, Watanabe Sumio, Toyoshima Itaru

机构信息

Department of Neurology, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.

出版信息

No To Shinkei. 2006 Apr;58(4):311-7.

Abstract

Pleurocybella porrigens related encephalopathy exhibits consciousness disturbance and convulsion in the patients after taking and patients show bilateral basal ganglia lesion resulted in high mortality rate. This encephalopathy is a very similar to the moldy sugarcane encephalopathy epidemic in China in the past. We investigated the relationship between Pleurocybella porrigens related encephalopathy and 3-nitropropionic acid which had caused the moldy sugarcane encephalopathy. We have tried to detect 3-NPA in the various specimens from patients and Pleurocybella porrigens, but failed. Further examinations for elucidating the causation of Pleurocybella porrigens related encephalopathy are needed.

摘要

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