Obara Koji, Wada Chizu, Yoshioka Toshiaki, Enomoto Katsuhiko, Yagishita Saburo, Toyoshima Itaru
Department of Neurology and Medical Education Center, Akita University School of Medicine, Akita, Japan.
Neuropathology. 2008 Apr;28(2):151-6. doi: 10.1111/j.1440-1789.2007.00819.x.
The authors report an autopsy case of acute encephalopathy in which generalized convulsion and coma occurred after ingestion of Pleurocybella porrigens (angel's wing mushroom). The patient was a 65-year-old man who had undergone hemodialysis for 3 months due to chronic renal failure. Pathologic examination of the brain revealed extensive postinfarction-like cystic necrosis in the bilateral putamens and multiple spotty necroses in the deep cerebral and cerebellar cortices. In 2004, similar acute encephalopathy related to ingestion of the mushroom was endemic in Japan, the pathogenesis of which remains to be elucidated.
作者报告了一例急性脑病的尸检病例，该患者在食用长根侧耳（天使翅膀蘑菇）后出现全身性惊厥和昏迷。患者为一名65岁男性，因慢性肾衰竭接受了3个月的血液透析。脑部病理检查显示双侧壳核广泛的梗死样囊性坏死以及大脑深部和小脑皮质多处点状坏死。2004年，日本曾出现与食用这种蘑菇相关的类似急性脑病的流行，其发病机制仍有待阐明。
