ICTI 联盟的描述：沙眼衣原体感染研究的综合方法。

Description of the ICTI consortium: an integrated approach to the study of Chlamydia trachomatis infection.

作者信息

Morré S A, Spaargaren J, Ossewaarde J M, Land J A, Bax C J, Dörr P J, Oostvogel P M, Vanrompay D, Savelkoul P H M, Pannekoek Y, van Bergen J E A M, Fennema H S A, de Vries H J, Crusius J B A, Peña A S, Ito J I, Lyons J M

机构信息

Laboratory of Immunogenetics, Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Drugs Today (Barc). 2006 Mar;42 Suppl A:107-14.

PMID:16683050

Abstract

The use of an integrated approach to the study of Chlamydia trachomatis infection of the female genital tract, presented at the mini-symposium "Chlamydia trachomatis infections" and described in the thesis of Joseph M. Lyons, has resulted in the creation of the ICTI consortium. The ICTI consortium is based on strong interaction and collaboration between basic scientists, clinicians, epidemiologists, and health care policy makers. This translational approach will help to further the valuable insight into the immunopathogenesis of this sexually transmitted infection (STI) and the development of new intervention strategies, including the vaccines and screening programs necessary to effectively diagnose, treat and prevent C. trachomatis infection. A background of the need for this integrated approach is presented and the goals and participants of the consortium are described.

摘要

在“沙眼衣原体感染”小型研讨会上展示并在约瑟夫·M·莱昂斯的论文中描述的对女性生殖道沙眼衣原体感染采用综合研究方法，促成了衣原体感染与干预联盟（ICTI）的成立。ICTI联盟基于基础科学家、临床医生、流行病学家和医疗保健政策制定者之间的紧密互动与合作。这种转化医学方法将有助于进一步深入了解这种性传播感染（STI）的免疫发病机制，并推动新干预策略的开发，包括有效诊断、治疗和预防沙眼衣原体感染所需的疫苗和筛查项目。本文介绍了这种综合方法的必要性背景，并描述了联盟的目标和参与者。