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曼谷学童的呼吸道症状与肺功能

Respiratory symptoms and lung function in Bangkok school children.

作者信息

Langkulsen Uma, Jinsart Wanida, Karita Kanae, Yano Eiji

机构信息

International Postgraduate Program in Environmental Management NRC-EHWM Chulalongkorn University, Bangkok, Thailand.

出版信息

Eur J Public Health. 2006 Dec;16(6):676-81. doi: 10.1093/eurpub/ckl061. Epub 2006 May 9.

Abstract

BACKGROUND

Previous epidemiological studies have shown acute effects of ambient air pollutants in children with respiratory disorders.

METHODS

The chronic effects of air pollution in Bangkok children were investigated. Children aged 10-15 years were examined for lung functions using spirometry tests and for respiratory symptoms by the American Thoracic Society's Division of Lung Diseases (ATS-DLD-78-C) questionnaire during May-August 2004. Effects of residential area were estimated by multiple logistic regression analysis. Of the 878 children, 722 (82%) had completed lung function test and ATS-DLD questionnaire.

RESULTS

In children, who live in roadside (R) and general (G) areas with high (H) pollution, the prevalence of respiratory symptoms increased significantly [odds ratios (95% confidence interval) in HR and HG are 2.44 (1.21-4.93) and 2.60 (1.38-4.91), respectively]. Children with normal lung function were less observed in H- and M-polluted roadside and general area [HR, OR = 1.41 (95% CI 0.89-2.22); HG, 1.08 (0.71-1.64); and MR, 0.99 (0.63-1.57)]. Residential locations and family members were associated with the prevalence of respiratory symptoms, whereas factors such as the responder of ATS-DLD, gender, age, residential years, home size, parental smoking habits, use of air conditioners, and domestic pets were not associated. Age was associated with the impaired lung function, whereas others factors were not associated.

CONCLUSION

The prevalence of respiratory symptoms and impaired lung function were higher among children living in areas with high pollution than those in areas with low pollution.

摘要

背景

先前的流行病学研究已表明环境空气污染物对患有呼吸系统疾病的儿童有急性影响。

方法

对曼谷儿童空气污染的慢性影响进行了调查。在2004年5月至8月期间,对10至15岁的儿童使用肺活量测定法进行肺功能检查,并通过美国胸科学会肺部疾病分会(ATS-DLD-78-C)问卷调查呼吸系统症状。通过多因素逻辑回归分析评估居住区域的影响。在878名儿童中,722名(82%)完成了肺功能测试和ATS-DLD问卷。

结果

生活在高污染路边(R)和一般(G)区域的儿童,呼吸系统症状的患病率显著增加[HR和HG区域的优势比(95%置信区间)分别为2.44(1.21-4.93)和2.60(1.38-4.91)]。在高污染和中等污染的路边及一般区域,肺功能正常的儿童较少[HR区域,OR = 1.41(95%CI 0.89-2.22);HG区域,1.08(0.71-1.64);MR区域,0.99(0.63-1.57)]。居住地点和家庭成员与呼吸系统症状的患病率相关,而ATS-DLD问卷的应答者、性别、年龄、居住年限、房屋大小、父母吸烟习惯、空调使用情况和家养宠物等因素则无关联。年龄与肺功能受损相关,而其他因素无关联。

结论

生活在高污染地区的儿童呼吸系统症状的患病率和肺功能受损情况高于低污染地区的儿童。

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