Buadong Dongruethai, Jinsart Wanida, Funatagawa Ikuko, Karita Kanae, Yano Eiji
Interdepartment Graduate Program in Environmental Science, Graduate School, Chulalongkorn University, Bangkok, Thailand.
J Epidemiol. 2009;19(4):182-8. doi: 10.2188/jea.je20080047. Epub 2009 Jun 13.
The association between air pollution and cardiovascular diseases is well known, but previous studies only assessed mortality and hospital admissions in North America, Europe, and Northeast Asia. Few studies have been conducted in less-developed countries in regions with a tropical climate. This study evaluated whether short-term exposures to fine particulate matter (PM(10)) and ozone (O(3)) were associated with hospital visits for cardiovascular diseases (CVD; ICD-10th, I00-I99) in central Bangkok, Thailand.
Data from hospital records were obtained from 3 major government hospitals. All hospital visits were stratified by age group and category of CVD. Daily PM(10) and O(3) levels reported by the Pollution Control Department from April 2002 to December 2006 (1736 days) were used in a time-series analysis with a generalized additive model procedure.
Exposure on the previous day to PM(10) and O(3) had a positive association with hospital visits for CVD among elderly (>or=65 years) individuals. The increase in CVD hospital visits in this age group was 0.10% (95% CI, 0.03-0.19) with a 10 microg/m(3) increase in PM(10), and 0.50% (95% CI, 0.19-0.81) with an increase in O(3).
In central Bangkok, a short-term association was observed between increases in daily levels of PM(10) and O(3) and the number of daily emergency hospital visits for CVD, particularly among individuals aged >or=65 years.
空气污染与心血管疾病之间的关联已为人熟知,但以往研究仅评估了北美、欧洲和东北亚地区的死亡率及住院率。在热带气候地区的欠发达国家开展的研究较少。本研究评估了泰国曼谷市中心短期暴露于细颗粒物(PM10)和臭氧(O3)是否与心血管疾病(CVD;国际疾病分类第十版,I00 - I99)的就诊人次有关。
从3家主要政府医院获取医院记录数据。所有就诊人次按年龄组和心血管疾病类别进行分层。采用广义相加模型程序进行时间序列分析,使用了污染控制部门报告的2002年4月至2006年12月(1736天)的每日PM10和O3水平数据。
前一天暴露于PM10和O3与老年(≥65岁)个体的心血管疾病就诊人次呈正相关。该年龄组心血管疾病就诊人次的增加幅度为:PM10每增加10微克/立方米,增加0.10%(95%可信区间,0.03 - 0.19);O3增加时,增加0.50%(95%可信区间,0.19 - 0.81)。
在曼谷市中心,观察到每日PM10和O3水平升高与心血管疾病每日急诊就诊人次之间存在短期关联,尤其是在年龄≥65岁的个体中。