纤毛原生动物中发育控制的基因组重排
Developmentally controlled genomic rearrangements in ciliated protozoa.
作者信息
Klobutcher L A, Jahn C L
机构信息
Department of Biochemistry, University of Connecticut Health Center, Farmington 06030.
出版信息
Curr Opin Genet Dev. 1991 Oct;1(3):397-403. doi: 10.1016/s0959-437x(05)80306-5.
PMID:1668650
Abstract
The ciliated protozoa undergo an extensive genome reorganization during the course of forming a transcriptionally active macronucleus. The process includes numerous chromosome fragmentation and DNA breakage and rejoining events. Recent work indicates that transposable elements play a role in the process.
摘要
纤毛原生动物在形成转录活跃的大核过程中经历广泛的基因组重组。该过程包括大量的染色体片段化以及DNA断裂和重新连接事件。最近的研究表明，转座元件在这一过程中发挥作用。
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