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[支气管哮喘——明确过敏成分有多重要?]

[Bronchial asthma--how important is the clarification of the allergy component?].

作者信息

Stratakis Diana F

机构信息

Schwerpunkt Pneumologie der Medizinischen Klinik Innenstadt der LMU München.

出版信息

MMW Fortschr Med. 2006 Apr 20;148(16):30-3; quiz 34.

Abstract

Bronchial asthma is a chronic disease underlying which is an inflammatory cascade. Allergic reactions have an important role to play, in particular in the case of children and adolescents. An allergological investigation is of great importance in the initial diagnostic work-up of an atopic diathesis, and for the identification of the allergen. Exhaustive history-taking is the essential first measure in the stepped diagnostic approach. In-vivo and in-vitro tests such as the prick test and total IgE can provide information about the extent of the atopy as well as support for the clinical suspicion, but they are not proof of the presence or absence of a clinically relevant sensitization. Further allergological tests (e.g. provocative test) are usually indicated only in specific problems, and should remain the domain of the allergologist or pneumologist.

摘要

支气管哮喘是一种慢性病,其基础是炎症级联反应。过敏反应起着重要作用,尤其是在儿童和青少年中。过敏学检查在特应性素质的初始诊断评估以及过敏原鉴定中具有重要意义。详尽的病史采集是阶梯式诊断方法中必不可少的首要措施。体内和体外试验,如点刺试验和总IgE,可以提供有关特应性程度的信息,并支持临床怀疑,但它们并不能证明是否存在临床相关的致敏。进一步的过敏学检查(如激发试验)通常仅在特定问题中进行,并且应仍由过敏学家或肺科医生负责。

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