Corruble Emmanuelle, Falissard Bruno, Gorwood Philip
Department of Psychiatry, Assistance Publique-Hôpitaux de Paris, Bicêtre University Hospital, INSERM U 669, Paris XI University, 78 rue du General Leclerc, 94230 Le Kremlin Bicêtre, France.
Eur Psychiatry. 2006 Sep;21(6):364-6. doi: 10.1016/j.eurpsy.2006.03.006. Epub 2006 May 11.
A cross-sectional survey investigated the relationship between the number of previous depressive episodes and life events, testing the kindling hypothesis, in a sample of 13,377 treated patients with unipolar depression. A linear decline of average life events exposure is observed for more frequent past episodes, even when age, gender and severity are taken into account.
一项横断面调查在13377例接受治疗的单相抑郁症患者样本中,研究了既往抑郁发作次数与生活事件之间的关系,以检验点燃假说。即使考虑到年龄、性别和严重程度,对于既往发作更频繁的患者,平均生活事件暴露呈线性下降。