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Revisiting a hypothesis: the neurovascular unit as a link between major depression and neurodegenerative disorders.

作者信息

Rajkumar Ravi Philip

机构信息

Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education, Pondicherry, India.

出版信息

Front Cell Neurosci. 2024 Aug 2;18:1455606. doi: 10.3389/fncel.2024.1455606. eCollection 2024.

DOI:10.3389/fncel.2024.1455606
PMID:39157756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11327082/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6693/11327082/dc53c0875e04/fncel-18-1455606-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6693/11327082/dc53c0875e04/fncel-18-1455606-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6693/11327082/dc53c0875e04/fncel-18-1455606-g0001.jpg

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Pharmacol Res. 2024 Mar;201:107087. doi: 10.1016/j.phrs.2024.107087. Epub 2024 Jan 30.
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Higher Blood-brain barrier permeability in patients with major depressive disorder identified by DCE-MRI imaging.利用 DCE-MRI 成像技术识别出患有重度抑郁症患者的血脑屏障通透性增加。
Psychiatry Res Neuroimaging. 2024 Jan;337:111761. doi: 10.1016/j.pscychresns.2023.111761. Epub 2023 Nov 23.
3
Blood-brain barrier dysfunction mediated by the EZH2-Claudin-5 axis drives stress-induced TNF-α infiltration and depression-like behaviors.
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Is later-life depression a risk factor for Alzheimer's disease or a prodromal symptom: a study using post-mortem human brain tissue?晚年抑郁症是阿尔茨海默病的危险因素还是前驱症状:一项使用死后人脑组织的研究?
Alzheimers Res Ther. 2023 Sep 12;15(1):153. doi: 10.1186/s13195-023-01299-2.
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Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation.慢性社会挫败会改变与大脑血管相关的细胞基因表达模式,导致血管功能障碍和免疫系统激活。
J Neuroinflammation. 2023 Jun 28;20(1):154. doi: 10.1186/s12974-023-02827-5.
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