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[酒精与肝脏]

[Alcohol and the liver].

作者信息

Boroń P

出版信息

Pol Tyg Lek. 1991;46(14-16):247-50.

PMID:1669043
Abstract

A biologic role of ethyl alcohol is analysed. The function of the liver in alcohol metabolism (90% of the total intake) in three oxidizing systems with the use of alcohol dehydrogenase, microsomal ethanol oxidizing system, and H2O2 catalase is described. Epidemiological data are given, clinical course of the alcohol-produced lesions to the liver starting from fatty degeneration, through the acute and chronic hepatitis, alcohol-produced cirrhosis up to the primary cancer of the liver are also presented in the light of authors experience.

摘要

分析了乙醇的生物学作用。描述了肝脏在酒精代谢(占总摄入量的90%)中的功能,该代谢过程通过使用乙醇脱氢酶、微粒体乙醇氧化系统和过氧化氢酶在三个氧化系统中进行。给出了流行病学数据,并根据作者的经验阐述了酒精对肝脏造成损害的临床过程,从脂肪变性开始,历经急性和慢性肝炎、酒精性肝硬化直至原发性肝癌。

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