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[β-肾上腺素能阻滞剂在孕妇甲状腺功能亢进治疗中的应用]

[Use of beta-adrenolytics in treatment of hyperthyroidism in pregnant women].

作者信息

Pisarek-Miedzińska D, Czech W

机构信息

Kliniki Ginekologiczno-Połozniczej.

出版信息

Pol Tyg Lek. 1991;46(17-18):323-4.

PMID:1669064
Abstract

Use of propranolol in the treatment of hyperthyreosis in pregnant women is discussed. It was noted, that propranolol given for 24-28 days in low doses, starting from the 34th-35th week of pregnancy, and in higher doses during 5 or 2 days preceding labour diminishes clinical symptoms of hyperthyreosis. It influences thyreotropic hormone levels. No side effects were seen in neonates of mothers treated with propranolol; thyreotrophic hormone levels were within normal values.

摘要

讨论了普萘洛尔在治疗孕妇甲状腺功能亢进症中的应用。值得注意的是,从妊娠第34 - 35周开始,低剂量给予普萘洛尔24 - 28天,并在分娩前5天或2天给予较高剂量,可减轻甲状腺功能亢进症的临床症状。它会影响促甲状腺激素水平。接受普萘洛尔治疗的母亲所生的新生儿未出现副作用;促甲状腺激素水平在正常范围内。

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