Kotlarek-Haus S, Kuliszkiewicz-Janus M, Potoczek S
Katedry i Kliniki Hematologii AM, Wrocławiu.
Pol Tyg Lek. 1991;46(17-18):325-8.
Sixty two women with Hodgkin's disease were questioned about disorders in their menstrual cycle and fertility. Menstrual cycle disorders were noted by 38 respondents, i.e. over 60%. Amenorrhoea persisted in 24 of these women. These disorders were significantly more frequent in patient over 30 year of age. There were 52 labours in the group of 38 women with menstrual cycle disorders prior to them, and 21 labours in a group of 24 women without any abnormalities. Hodgkin's disease was diagnosed in 6 patients during pregnancy: 2 of them were treated with irradiations on the upper part of the body while 4 remained untreated. After radiotherapy, there were 2 deliveries in women of the group with menstrual cycle disorders, and 9 deliveries in women without such disturbances. Answers to the supplied questionnaire did not provide any information on the congenital abnormalities in neonates.
对62名霍奇金病女性患者就其月经周期紊乱和生育能力方面的问题进行了询问。38名受访者(即超过60%)指出存在月经周期紊乱。其中24名女性持续闭经。这些紊乱在30岁以上的患者中明显更为常见。在38名月经周期紊乱的女性组中有52次分娩,而在24名无任何异常的女性组中有21次分娩。6名患者在怀孕期间被诊断出患有霍奇金病:其中2人接受了上半身放疗,4人未接受治疗。放疗后,月经周期紊乱组的女性中有2例分娩,无此类紊乱的女性中有9例分娩。所提供问卷的答案未提供任何关于新生儿先天性异常的信息。