Tang Wai Kwong, Chan Sandra S M, Chiu Helen F K, Ungvari Gabor S, Wong Ka Sing, Kwok Timothy C Y, Mok Vincent, Wong K T, Richards Polly S, Ahuja Anil T
Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China.
J Geriatr Psychiatry Neurol. 2006 Jun;19(2):65-71. doi: 10.1177/0891988706286230.
The objective of this study was to examine the prevalence and clinical correlates of poststroke cognitive impairment in Chinese stroke patients in Hong Kong. One hundred seventy-nine stroke patients were interviewed by a psychiatrist 3 months after their stroke. Cognitive impairment was determined according to the Mini-Mental State Examination score. Thirty-nine participants (21.8%) had cognitive impairment. Univariate analysis found that cognitive impairment was associated with age, female sex, level of education, previous stroke, prestroke Rankin score, National Institutes of Health Stroke Scale dysarthria and total scores, urinary incontinence, and cerebral atrophy index. Multivariate logistic regression suggested that female sex, education, National Institutes of Health Stroke Scale dysarthria score, urinary incontinence, and atrial fibrillation were independent risk factors of poststroke cognitive impairment. After removal of 54 patients with previous stroke from the sample, the frequency of cognitive impairment decreased to 18.4%. It was concluded that cognitive impairment is common among nondemented Chinese stroke patients in Hong Kong.
本研究的目的是调查香港中国卒中患者卒中后认知障碍的患病率及其临床相关因素。179例卒中患者在卒中后3个月接受了精神科医生的访谈。根据简易精神状态检查表评分确定认知障碍情况。39名参与者（21.8%）存在认知障碍。单因素分析发现，认知障碍与年龄、女性性别、教育程度、既往卒中史、卒中前Rankin评分、美国国立卫生研究院卒中量表构音障碍及总分、尿失禁和脑萎缩指数有关。多因素logistic回归分析提示，女性性别、教育程度、美国国立卫生研究院卒中量表构音障碍评分、尿失禁和心房颤动是卒中后认知障碍的独立危险因素。从样本中剔除54例有既往卒中史的患者后，认知障碍的发生率降至18.4%。研究得出结论，在香港非痴呆的中国卒中患者中，认知障碍很常见。
