Cook Andrew J, Degood Douglas E
Department of Anesthesiology, Division of Pain , University of Virginia Health System, Charlottesville, VA 22908, USA.
Clin J Pain. 2006 May;22(4):332-45. doi: 10.1097/01.ajp.0000209801.78043.91.
An extensive body of research suggests that maladaptive beliefs about chronic pain can have a negative impact on patient adherence and treatment response. A series of studies to develop and validate a clinically-based, self-report instrument for pain beliefs, the Cognitive Risk Profile for Pain (CRPP), was undertaken. We sought to expand the existing body of knowledge for pain beliefs by development of an instrument with a somewhat different content and format than prior pain belief measures, and a primary focus on clinical risk assessment for treatment planning.
Test development and evaluation procedures were applied in the initial stages of CRPP development. We report here on a series of studies to evaluate and refine the structure and content of the CRPP, and to establish its internal reliability, concurrent, and criterion validities. A 68-item version of the CRPP was evaluated, including a total risk score and 9 scale scores: philosophic beliefs about pain (PB), denial that mood affects pain (MP), denial that pain affects mood (PM), perception of blame (BL), inadequate support (IS), disability entitlement (DE), desire for medical breakthrough (MB), skepticism of multidisciplinary approach (SM), and conviction of hopelessness (CH). The CRPP was administered to two large samples of chronic pain outpatients (n=499; 125) in conjunction with other self-report scales for pain and associated beliefs, behaviors, and psychopathology. In a final study, treatment outcome measures were obtained for a subsample of chronic pain patients (n=91) to evaluate criterion validity.
Confirmatory factor analyses showed improved fit for the CRPP scale structure after elimination of 15 items. The resulting 53-item CRPP was found to have good internal consistency for the full score (alpha=0.82) and 7 of 9 scales, with moderate consistency for scales BL and MB. Low to moderate scale intercorrelations were found. Correlations with pain and psychosocial measures suggested good construct validity for the majority of individual scales and total score. Results were inconsistent for scale MP. Multivariate analyses of variances (MANOVAs) based on tertile split of total risk scores showed significant main effects across pain, mood, productivity, and sleep ratings at 3 and 6-month treatment follow-ups. Analyses of clinically significant treatment changes (ie, 2 points on a 11-point Numerical Rating Scales) showed significantly higher prevalence of treatment "failures" at 6 months among CRPP high-risk patients, but no significant differences at 3 months.
Results provide initial support for the CRPP as a reliable, valid, and useful measure of general cognitive risk for pain management. Results were supportive of the content and reliabilities of the majority of scale scores. Scales for denial of mood impact on pain, perception of blame, and desire for medical breakthrough will require further evaluation. Data indicate an association of CRPP total risk with multidimensional outcome from medical treatment of chronic pain, supporting relevance to treatment planning. The unique content and format of the CRPP may be useful in some clinical pain settings. Possible applications of the CRPP for risk assessment and treatment planning for chronic pain are discussed.
大量研究表明,对慢性疼痛的适应不良信念会对患者的依从性和治疗反应产生负面影响。我们开展了一系列研究,以开发并验证一种基于临床的、用于疼痛信念的自我报告工具——疼痛认知风险概况(CRPP)。我们试图通过开发一种内容和形式与以往疼痛信念测量方法略有不同、主要侧重于治疗计划临床风险评估的工具,来扩充现有的疼痛信念知识体系。
在CRPP开发的初始阶段应用了测试开发和评估程序。我们在此报告一系列研究,以评估和完善CRPP的结构和内容,并确定其内部信度、同时效度和效标效度。对CRPP的一个68项版本进行了评估,包括一个总风险得分和9个量表得分:关于疼痛的哲学信念(PB)、否认情绪影响疼痛(MP)、否认疼痛影响情绪(PM)、责备感(BL)、支持不足(IS)、残疾权益(DE)、对医学突破的渴望(MB)、对多学科方法的怀疑(SM)以及绝望信念(CH)。将CRPP与其他关于疼痛及相关信念、行为和精神病理学的自我报告量表一起施用于两组慢性疼痛门诊患者的大样本(n = 499;125)。在最后一项研究中,获取了慢性疼痛患者子样本(n = 91)的治疗结果测量值,以评估效标效度。
验证性因素分析表明,在剔除15个项目后,CRPP量表结构的拟合度有所提高。结果得到的53项CRPP在总分(α = 0.82)和9个量表中的7个量表上具有良好的内部一致性,BL和MB量表的一致性中等。发现量表间的相关性较低至中等。与疼痛和心理社会测量的相关性表明,大多数单个量表和总分具有良好的结构效度。MP量表的结果不一致。基于总风险得分三分位数划分的多变量方差分析(MANOVA)显示,在3个月和6个月的治疗随访中,在疼痛、情绪、生产力和睡眠评分方面存在显著的主效应。对具有临床意义的治疗变化(即11点数字评分量表上2分的变化)的分析表明,CRPP高风险患者在6个月时治疗“失败”的发生率显著更高,但在3个月时无显著差异。
结果为CRPP作为一种可靠、有效且有用的疼痛管理总体认知风险测量方法提供了初步支持。结果支持了大多数量表得分的内容和信度。否认情绪对疼痛的影响、责备感和对医学突破的渴望等量表需要进一步评估。数据表明CRPP总风险与慢性疼痛医学治疗的多维度结果相关,支持其与治疗计划的相关性。CRPP独特的内容和形式可能在某些临床疼痛环境中有用。讨论了CRPP在慢性疼痛风险评估和治疗计划中的可能应用。