Pawlowski Rafał, Jura Jolanta
Department of Cell Biochemistry, Faculty of Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387, Krakow, Poland.
Mol Cell Biochem. 2006 Aug;288(1-2):159-69. doi: 10.1007/s11010-006-9133-7. Epub 2006 May 12.
Liver possesses the capacity to restore its tissue mass and attain optimal volume in response to physical, infectious and toxic injury. The extraordinary ability of liver to regenerate is the effect of cross-talk between growth factors, cytokines, matrix components and many other factors. In this review we present recent findings and existing information about mechanisms that regulate liver growth, paying attention to augmenter of liver regeneration.
肝脏具有在受到物理、感染和毒性损伤时恢复其组织质量并达到最佳体积的能力。肝脏非凡的再生能力是生长因子、细胞因子、基质成分和许多其他因素之间相互作用的结果。在这篇综述中,我们介绍了有关调节肝脏生长机制的最新发现和现有信息,重点关注肝脏再生增强因子。