Viano J C, Tregnaghi M, Casagnas M, Suárez J C
Department of Neurosurgery, Municipal Infantile Hospital, Cordoba, Argentina.
Childs Nerv Syst. 1990 Nov;6(7):397-9. doi: 10.1007/BF00302226.
Shunt infections in children have become a serious problem. In order to solve this, we have been using antibiotic therapy with Rifampicin (Rifampin) for the last 2 years; the dosage is 20 mg/kg per day 1 h before surgery and then for 48 h after the surgical procedure. We have had experience with 203 children operated on between January 1987 and December 1988. The result was a significant decrease in the number of children with shunt infections. In 1980 we reported an incidence of 10%, while by 1988 the rate had gone down to 1%.
儿童分流感染已成为一个严重问题。为了解决这一问题，在过去两年里我们一直在使用利福平进行抗生素治疗；剂量为每天20毫克/千克，在手术前1小时服用，然后在手术后服用48小时。我们对1987年1月至1988年12月期间接受手术的203名儿童有相关经验。结果是分流感染儿童的数量显著减少。1980年我们报告的发病率为10%，而到1988年这一比率已降至1%。
