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1
CHEMICAL, CLINICAL AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION: XXXII. THE COAGULATION DEFECT IN HEMOPHILIA. AN IN VITRO AND IN VIVO COMPARISON OF NORMAL AND HEMOPHILIC WHOLE BLOOD, PLASMA AND DERIVED PLASMA PROTEIN FRACTIONS.人血浆成分制品的化学、临床及免疫学研究：XXXII. 血友病中的凝血缺陷。正常与血友病全血、血浆及衍生血浆蛋白组分的体外和体内比较。
J Clin Invest. 1946 Nov;25(6):870-5. doi: 10.1172/JCI101774.
2
Chemical, clinical and immunological studies on the products of human plasma fractionation; the coagulation defect in hemophilia; an in vitro and in vivo comparison of normal and hemophilic whole blood, plasma and derived plasma protein fractions.人血浆分馏产物的化学、临床及免疫学研究；血友病中的凝血缺陷；正常及血友病全血、血浆和衍生血浆蛋白组分的体外及体内比较。
J Clin Invest. 1946 Nov;25(6):870-5.
3
Chemical, clinical and immunological studies on the products of human plasma fractionation; the coagulation defect in hemophilia; the effect in vitro and in vivo on the coagulation time in hemophilia of a prothrombin and fibrinogen-free normal plasma and its derived protein fractions.人血浆成分制品的化学、临床及免疫学研究；血友病的凝血缺陷；无凝血酶原和纤维蛋白原的正常血浆及其衍生蛋白组分对血友病患者体内外凝血时间的影响。
J Clin Invest. 1946 Nov;25(6):876-9.
4
CHEMICAL, CLINICAL AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXXIII. THE COAGULATION DEFECT IN HEMOPHILIA: THE EFFECT IN VITRO AND IN VIVO ON THE COAGULATION TIME IN HEMOPHILIA OF A PROTHROMBIN AND FIBRINOGEN-FREE NORMAL PLASMA AND ITS DERIVED PROTEIN FRACTIONS.人血浆成分制品的化学、临床及免疫学研究。三十三。血友病的凝血缺陷：无凝血酶原和纤维蛋白原的正常血浆及其衍生蛋白组分对血友病患者体外和体内凝血时间的影响。
J Clin Invest. 1946 Nov;25(6):876-9. doi: 10.1172/JCI101775.
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The pathogenesis of hemophilia; an experimental analysis of the anticephalin hypothesis in hemophilic dogs.血友病的发病机制；对血友病犬抗脑磷脂假说的实验分析。
J Exp Med. 1957 Aug 1;106(2):273-92. doi: 10.1084/jem.106.2.273.
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[Effect of dilution on coagulation of plasma in vitro (normal coagulation, retarded coagulation and hemophilic coagulation].[稀释对体外血浆凝固的影响（正常凝血、延迟凝血和血友病凝血）]
Sang. 1950;21(8):732-40.
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The defect in hemophilic and von Willebrand's disease plasmas studied by a recombination technique.通过重组技术研究血友病和血管性血友病血浆中的缺陷。
J Clin Invest. 1974 Nov;54(5):1093-9. doi: 10.1172/JCI107853.
8
THE COAGULATION DEFECT IN HEMOPHILIA: A COMPARISON OF THE PROTEOLYTIC ACTIVITY OF CHLOROFORM PREPARATIONS OF HEMOPHILIC AND NORMAL HUMAN PLASMA.血友病中的凝血缺陷：血友病患者与正常人血浆氯仿制剂的蛋白水解活性比较。
J Clin Invest. 1943 Jan;22(1):127-9. doi: 10.1172/JCI101363.
9
Human factor IX corrects the bleeding diathesis of mice with hemophilia B.人凝血因子IX可纠正B型血友病小鼠的出血倾向。
Blood. 1998 Feb 1;91(3):784-90.
10
[Hemophilic syndrome: effect of lyophilized plasma and effect of serum fractions on coagulation in vitro].[血友病综合征：冻干血浆的作用及血清组分对体外凝血的作用]
Prog Med (Napoli). 1954 Jan 31;10(2):47-53.

引用本文的文献

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Serum Proteins: A Review.血清蛋白：综述
J Clin Pathol. 1949 Aug;2(3):161-92. doi: 10.1136/jcp.2.3.161.
2
STUDIES OF HEMOPHILIA. II. THE ASSAY OF THE ANTIHEMOPHILIC CLOT-PROMOTING PRINCIPLE IN NORMAL HUMAN PLASMA WITH SOME OBSERVATIONS ON THE RELATIVE POTENCY OF CERTAIN PLASMA FRACTIONS.血友病研究。II. 正常人血浆中抗血友病促凝因子的测定及对某些血浆组分相对效力的一些观察。
J Clin Invest. 1948 Jan;27(1):98-105. doi: 10.1172/JCI101929.
3
The aetiology and diagnosis of haemorrhagic diseases in children.儿童出血性疾病的病因学与诊断
Postgrad Med J. 1951 Sep;27(311):453-62. doi: 10.1136/pgmj.27.311.453.

本文引用的文献

1
THE COAGULATION DEFECT IN HEMOPHILIA: THE EFFECT, IN HEMOPHILIA, OF THE PARENTERAL ADMINISTRATION OF A FRACTION OF THE PLASMA GLOBULINS RICH IN FIBRINOGEN.血友病中的凝血缺陷：血友病患者注射富含纤维蛋白原的血浆球蛋白组分的效果。
J Clin Invest. 1945 Sep;24(5):704-7. doi: 10.1172/JCI101654.
2
STUDIES IN BLOOD COAGULATION: THE COAGULATION PROPERTIES OF CERTAIN GLOBULIN FRACTIONS OF NORMAL HUMAN PLASMA IN VITRO.血液凝固研究：正常人血浆某些球蛋白组分在体外的凝固特性
J Clin Invest. 1945 Sep;24(5):698-703. doi: 10.1172/JCI101653.
3
THE COAGULATION DEFECT IN HEMOPHILIA: A COMPARISON OF THE PROTEOLYTIC ACTIVITY OF CHLOROFORM PREPARATIONS OF HEMOPHILIC AND NORMAL HUMAN PLASMA.血友病中的凝血缺陷：血友病患者与正常人血浆氯仿制剂的蛋白水解活性比较。
J Clin Invest. 1943 Jan;22(1):127-9. doi: 10.1172/JCI101363.
4
THE COAGULATION DEFECT IN HEMOPHILIA: THE CLOT PROMOTING ACTIVITY IN HEMOPHILIA OF BERKEFELDED NORMAL HUMAN PLASMA FREE FROM FIBRINOGEN AND PROTHROMBIN.血友病中的凝血缺陷：不含纤维蛋白原和凝血酶原的伯克费尔德正常人血浆在血友病中的促凝活性。
J Clin Invest. 1939 Sep;18(5):603-8. doi: 10.1172/JCI101074.
5
THE COAGULATION DEFECT IN HEMOPHILIA. THE EFFECT IN HEMOPHILIA OF INTRAMUSCULAR ADMINISTRATION. OF A GLOBULIN SUBSTANCE DERIVED FROM NORMAL HUMAN PLASMA.血友病中的凝血缺陷。正常人血浆来源的球蛋白物质肌肉注射对血友病的影响。
J Clin Invest. 1937 Sep;16(5):741-7. doi: 10.1172/JCI100899.
6
HEMOPHILIA. II. SOME PROPERTIES OF A SUBSTANCE OBTAINED FROM NORMAL HUMAN PLASMA EFFECTIVE IN ACCELERATING THE COAGULATION OF HEMOPHILIC BLOOD.血友病。二、从正常人血浆中提取的一种物质的某些特性，该物质能有效加速血友病患者血液的凝固。
J Clin Invest. 1937 Jan;16(1):113-24. doi: 10.1172/JCI100829.
7
HEMOPHILIA. I. THE ABNORMAL COAGULATION OF THE BLOOD AND ITS RELATION TO THE BLOOD PLATELETS.血友病。一、血液的异常凝血及其与血小板的关系。
J Clin Invest. 1936 Sep;15(5):531-42. doi: 10.1172/JCI100806.

CHEMICAL, CLINICAL AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION: XXXII. THE COAGULATION DEFECT IN HEMOPHILIA. AN IN VITRO AND IN VIVO COMPARISON OF NORMAL AND HEMOPHILIC WHOLE BLOOD, PLASMA AND DERIVED PLASMA PROTEIN FRACTIONS.

作者信息

Lewis J H, Davidson C S, Minot G R, Soulier J P, Tagnon H J, Taylor F H

机构信息

Thorndike Memorial Laboratory, Second and Fourth Medical Services, Boston City Hospital, Boston.

出版信息

J Clin Invest. 1946 Nov;25(6):870-5. doi: 10.1172/JCI101774.

DOI:10.1172/JCI101774
PMID:16695384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC435632/
Abstract
摘要