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STUDIES ON AMINO ACID METABOLISM. II. BLOOD GLYCINE AND TOTAL AMINO ACIDS IN VARIOUS PATHOLOGICAL CONDITIONS, WITH OBSERVATIONS ON THE EFFECTS OF INTRAVENOUSLY ADMINISTERED GLYCINE.

作者信息

de Vries A, Alexander B, Quamo Y

机构信息

Medical Research Laboratory, Beth Israel Hospital, Boston.

出版信息

J Clin Invest. 1948 Sep;27(5):655-64. doi: 10.1172/JCI102013.

DOI:10.1172/JCI102013
PMID:16695586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC439538/
Abstract
摘要

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1
STUDIES ON AMINO ACID METABOLISM. II. BLOOD GLYCINE AND TOTAL AMINO ACIDS IN VARIOUS PATHOLOGICAL CONDITIONS, WITH OBSERVATIONS ON THE EFFECTS OF INTRAVENOUSLY ADMINISTERED GLYCINE.氨基酸代谢研究。II. 各种病理状况下的血液甘氨酸和总氨基酸，并观察静脉注射甘氨酸的效果。
J Clin Invest. 1948 Sep;27(5):655-64. doi: 10.1172/JCI102013.
2
Studies on amino acid metabolism; blood glycine and total amino acids in various pathological conditions, with observations on the effects of intravenously administered glycine.氨基酸代谢研究；各种病理状态下血液中的甘氨酸和总氨基酸，并观察静脉注射甘氨酸的效果。
J Clin Invest. 1948 Sep;27(5):655-64.
3
Studies of amino acid metabolism; blood glycine and alanine and their relationship to the total amino acids in normal subjects.氨基酸代谢研究；正常受试者血液中的甘氨酸和丙氨酸及其与总氨基酸的关系。
J Biol Chem. 1947 May;168(2):527-36.
4
Design and evaluation by nitrogen balance and blood aminograms of an amino acid mixture for total parenteral nutrition of adults with gastrointestinal disease.通过氮平衡和血液氨基酸谱对用于胃肠道疾病成人全胃肠外营养的氨基酸混合物进行设计与评估。
J Clin Invest. 1974 Mar;53(3):904-12. doi: 10.1172/JCI107631.
5
FURTHER OBSERVATIONS ON THE AMINO ACID REQUIREMENTS OF OLDER MEN. I. EFFECTS OF NONESSENTIAL NITROGEN SUPPLEMENTS FED WITH DIFFERENT AMOUNTS OF ESSENTIAL AMINO ACIDS.关于老年男性氨基酸需求的进一步观察。I. 不同必需氨基酸摄入量下非必需氮补充剂的影响。
Am J Clin Nutr. 1965 Feb;16:225-8. doi: 10.1093/ajcn/16.2.225.
6
Metabolism of steroid and amino acid moieties of conjugated bile acids in man. II. Glycine-conjugated dihydroxy bile acids.人体内结合胆汁酸的类固醇和氨基酸部分的代谢。II. 甘氨酸结合的二羟基胆汁酸。
J Clin Invest. 1972 Jul;51(7):1898-905. doi: 10.1172/JCI106992.
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Influence of amino acids on gastric adaptive relaxation (accommodation) in rats as evaluated with a barostat.用压力传感器评估氨基酸对大鼠胃适应性舒张（容纳功能）的影响。
J Smooth Muscle Res. 2016;52(0):56-65. doi: 10.1540/jsmr.52.56.
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Metabolism of intravenously administered dipeptides in rats: effects on amino acid pools, glucose concentration and insulin and glucagon secretion.大鼠静脉注射二肽的代谢：对氨基酸池、葡萄糖浓度以及胰岛素和胰高血糖素分泌的影响。
Clin Sci Mol Med. 1977 Feb;52(2):193-204. doi: 10.1042/cs0520193.
9
Equilibration of 15N-labeled amino compounds in man.人体中15N标记氨基化合物的平衡
Am J Physiol. 1976 May;230(5):1326-30. doi: 10.1152/ajplegacy.1976.230.5.1326.
10
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.谷氨酸、γ-氨基丁酸、甘氨酸和牛磺酸可调节原代培养中延髓吻侧和尾侧缝际核细胞中5-羟色胺的合成与释放。
Neurochem Int. 1993 Sep;23(3):269-83. doi: 10.1016/0197-0186(93)90118-o.

引用本文的文献

1
STUDIES ON AMINO ACID METABOLISM. III. PLASMA GLYCINE CONCENTRATION AND HIPPURIC ACID FORMATION FOLLOWING THE INGESTION OF BENZOATE.氨基酸代谢研究。III. 摄入苯甲酸盐后血浆甘氨酸浓度及马尿酸形成情况
J Clin Invest. 1948 Sep;27(5):665-8. doi: 10.1172/JCI102014.
2
Studies in para-aminohippuric acid synthesis in the human: its application as a liver function test.人体对氨基马尿酸合成的研究：其作为肝功能测试的应用。
J Clin Invest. 1950 Aug;29(8):1014-20. doi: 10.1172/JCI102332.
3
Hippuric acid synthesis in the rat.大鼠体内马尿酸的合成
Biochem J. 1951 Dec;50(2):154-62. doi: 10.1042/bj0500154.
4
[Study of the glycocoll levels in blood and urine].[血液和尿液中甘氨酸水平的研究]
Klin Wochenschr. 1951 Apr 15;29(15-16):285-90. doi: 10.1007/BF01477122.
5
[The influence of toxic liver damage on the spectrum of free flood amino acids].[毒性肝损伤对游离血浆氨基酸谱的影响]
Klin Wochenschr. 1963 May 1;41:441-7. doi: 10.1007/BF01483309.
6
[Research on the serotonin metabolism and its preliminary stage, 5-hydroxytryptophan, in normal persons and liver patients].[正常人和肝病患者血清素代谢及其初级阶段5-羟色氨酸的研究]
Klin Wochenschr. 1962 Dec 15;40:1229-33. doi: 10.1007/BF01484387.
7
The levels of individual free amino acids in the plasma of normal man at various intervals after a high-protein meal.高蛋白餐后不同时间间隔正常男性血浆中各游离氨基酸的水平。
J Clin Invest. 1958 Dec;37(12):1710-23. doi: 10.1172/JCI103763.
8
Apparent free amino acids in deproteinized plasma of normal and uremic persons.正常人和尿毒症患者去蛋白血浆中的表观游离氨基酸。
J Clin Invest. 1957 Aug;36(8):1227-32. doi: 10.1172/JCI103519.
9
Abnormal glycine metabolism in rheumatoid arthritis.类风湿关节炎中异常的甘氨酸代谢
J Clin Invest. 1952 Nov;31(11):993-9. doi: 10.1172/JCI102693.

本文引用的文献

1
STUDIES ON AMINO ACID METABOLISM. III. PLASMA GLYCINE CONCENTRATION AND HIPPURIC ACID FORMATION FOLLOWING THE INGESTION OF BENZOATE.氨基酸代谢研究。III. 摄入苯甲酸盐后血浆甘氨酸浓度及马尿酸形成情况
J Clin Invest. 1948 Sep;27(5):665-8. doi: 10.1172/JCI102014.
2
EFFECTS OF THYROID ON CREATINE METABOLISM WITH A DISCUSSION OF THE MECHANISM OF STORAGE AND EXCRETION OF CREATINE BODIES.甲状腺对肌酸代谢的影响，并对肌酸物质的储存及排泄机制进行讨论。
J Clin Invest. 1946 May;25(3):360-77. doi: 10.1172/JCI101717.
3
STUDIES ON THE CREATINURIA DUE TO METHYLATED STEROIDS.甲基化甾体所致肌酸尿症的研究
J Clin Invest. 1945 Jan;24(1):21-32. doi: 10.1172/JCI101574.
4
AMINO ACID STUDIES. II. PLASMA AMINO ACID RETENTION, AS EVIDENCE OF IMPAIRED LIVER FUNCTION. INVESTIGATIONS IN CHILDREN WITH NEPHROSIS AND LIVER DISEASE.氨基酸研究。II. 血浆氨基酸潴留，作为肝功能受损的证据。对肾病和肝病患儿的调查。
J Clin Invest. 1943 Mar;22(2):169-81. doi: 10.1172/JCI101380.
5
THE GLYCINE TOLERANCE TEST IN SPRUE AND PERNICIOUS ANEMIA.口炎性腹泻和恶性贫血中的甘氨酸耐量试验
J Clin Invest. 1940 Mar;19(2):409-21. doi: 10.1172/JCI101143.
6
THE CHEMICAL COMPOSITION OF VOLUNTARY MUSCLE IN MUSCLE DISEASE: A COMPARISON OF PROGRESSIVE MUSCULAR DYSTROPHY WITH OTHER DISEASES TOGETHER WITH A STUDY OF EFFECTS OF GLYCINE AND CREATINE THERAPY.肌肉疾病中随意肌的化学成分：进行性肌营养不良与其他疾病的比较以及甘氨酸和肌酸治疗效果的研究
J Clin Invest. 1938 Jul;17(4):377-83. doi: 10.1172/JCI100963.
7
THE GLYCINE SYNTHESIS IN PATIENTS WITH PROGRESSIVE MUSCULAR DYSTROPHY.进行性肌营养不良患者的甘氨酸合成
J Clin Invest. 1937 Mar;16(2):231-6. doi: 10.1172/JCI100852.
8
THE ABILITY OF NEPHRITIC PATIENTS TO DEAMINIZE AND FORM UREA FROM INGESTED GLYCINE.肾炎患者对摄入甘氨酸进行脱氨基作用并形成尿素的能力。
J Clin Invest. 1935 Jan;14(1):136-41. doi: 10.1172/JCI100649.
9
AMINO NITROGEN CHANGES OF THE BLOOD IN NEPHRITIS.肾炎时血液中氨基氮的变化
J Clin Invest. 1933 Nov;12(6):1091-102. doi: 10.1172/JCI100560.