THE "INDUCTION" OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN.
作者信息
Bertino J R, Donohue D M, Simmons B, Gabrio B W, Silber R, Huennekens F M
机构信息
Department of Medicine, University of Washington and King County Blood Bank, Seattle, Wash.
出版信息
J Clin Invest. 1963 Apr;42(4):466-75. doi: 10.1172/JCI104735.
Abstract
摘要
相似文献
1
THE "INDUCTION" OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN.用氨甲蝶呤治疗的患者白细胞和红细胞中二氢叶酸还原酶活性的“诱导”
J Clin Invest. 1963 Apr;42(4):466-75. doi: 10.1172/JCI104735.
2
Dihydrofolic reductase in human blood cells. II. Enzyme activity after amethopterin and actinomycin C administration.人血细胞中的二氢叶酸还原酶。II. 给予氨甲蝶呤和放线菌素C后的酶活性
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3
Increased level of dihydrofolic reductase in leucocytes of patients treated with amethopterin.接受氨甲蝶呤治疗的患者白细胞中二氢叶酸还原酶水平升高。
Nature. 1962 Jan 13;193:140-2. doi: 10.1038/193140a0.
4
Inhibition of dihydrofolic reductase by aminopterin and amethopterin.氨蝶呤和甲氨蝶呤对二氢叶酸还原酶的抑制作用。
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5
Dihydrofolic reductase in human blood cells. I. Techniques for the study of enzyme activity and intracellular amethopterin content.人类血细胞中的二氢叶酸还原酶。I. 酶活性和细胞内氨甲蝶呤含量的研究技术。
Enzymol Biol Clin (Basel). 1967;8(5):353-62.
6
Isolation and characterization of dihydrofolic acid reductase from methotrexate-sensitive and -resistant human cell lines.从对甲氨蝶呤敏感和耐药的人类细胞系中分离和鉴定二氢叶酸还原酶
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Resistance of Pediococcus cerevisiae to amethopterin as a consequence of changes in enzymatic activity and cell permeability. I. Dihydrofolate reductase, thymidylate synthetase and formyltetrahydrofolate synthetase in amethopterin-resistant and -sensitive strains of Pediococcus cerevisiae.啤酒片球菌对氨甲蝶呤的抗性与酶活性和细胞通透性变化的关系。I. 啤酒片球菌氨甲蝶呤抗性和敏感菌株中的二氢叶酸还原酶、胸苷酸合成酶和甲酰四氢叶酸合成酶
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Folate-dependent enzymes in human epidermis. Tetrahydrofolate-dependent enzymes and relationship between dihydrofolic reductase and amethopterin.
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Separation of folic acid reductase from Streptococcus faecium (ATCC 8043).从粪肠球菌（ATCC 8043）中分离叶酸还原酶。
J Bacteriol. 1969 Mar;97(3):1160-4. doi: 10.1128/jb.97.3.1160-1164.1969.
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LEVELS OF DIHYDROFOLATE REDUCTASE AND THE FORMATE-ACTIVATING ENZYME ACTIVITIES IN GUINEA PIG TISSUES BEFORE AND AFTER AMETHOPTERIN ADMINISTRATION.氨甲蝶呤给药前后豚鼠组织中二氢叶酸还原酶水平及甲酸盐激活酶活性
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Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells.小鼠细胞DNA介导转化体中双微体染色体的共扩增、多药耐药性及细胞表面P-糖蛋白
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J Clin Invest. 1969 Nov;48(11):2140-55. doi: 10.1172/JCI106181.
7
[Effect and istribution of methotrexate in the human organism during leukemia treatment].[白血病治疗期间甲氨蝶呤在人体中的作用及分布]
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8
[Dihydrofolate reductase and thymidine kinase in the bone marrow under the influence of folic acid antagonists].[叶酸拮抗剂作用下骨髓中的二氢叶酸还原酶和胸苷激酶]
Klin Wochenschr. 1967 Oct 1;45(19):987-94. doi: 10.1007/BF01746131.
9
A haematological study of patients receiving long-term treatment with trimethoprim and sulphonamide.对接受甲氧苄啶和磺胺长期治疗的患者进行的血液学研究。
J Clin Pathol. 1970 Jul;23(5):392-6. doi: 10.1136/jcp.23.5.392.
10
[Determination, properties and inhibition of thymidilate synthetase in immature myeloid blood and bone marrow cells].[未成熟髓系血细胞和骨髓细胞中胸苷酸合成酶的测定、特性及抑制作用]
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本文引用的文献
1
On the mechanism of action of aminopterin.关于氨甲蝶呤的作用机制。
Proc Soc Exp Biol Med. 1950 Jun;74(2):403-11. doi: 10.3181/00379727-74-17922.
2
Erythrocyte metabolism. VI. Separation of erythrocyte enzymes from hemoglobin.红细胞代谢。VI. 从血红蛋白中分离红细胞酶。
J Clin Invest. 1962 Jun;41(6):1257-62. doi: 10.1172/JCI104588.
3
Leukemic cell proliferation as determined by in vitro deoxyribonucleic acid synthesis.通过体外脱氧核糖核酸合成测定的白血病细胞增殖。
J Clin Invest. 1962 Feb;41(2):360-9. doi: 10.1172/JCI104490.
4
Purification and properties of the formate-activating enzyme from erythrocytes.红细胞中甲酸激活酶的纯化及性质
J Biol Chem. 1962 Apr;237:1314-8.
5
Increased level of dihydrofolic reductase in leucocytes of patients treated with amethopterin.接受氨甲蝶呤治疗的患者白细胞中二氢叶酸还原酶水平升高。
Nature. 1962 Jan 13;193:140-2. doi: 10.1038/193140a0.
6
Studies on the nature of resistance of Streptococcus faecalis to folic acid antagonists.粪链球菌对叶酸拮抗剂耐药性本质的研究。
Biochem Pharmacol. 1959 Dec;3:1-9. doi: 10.1016/0006-2952(59)90002-4.
7
Evidence for a single enzyme reducing folate and dihydrofolate.
J Biol Chem. 1960 Oct;235:2984-8.
8
Interference with the feed-back control of histidine biosynthesis.对组氨酸生物合成反馈控制的干扰。
J Biol Chem. 1961 Aug;236:2261-7.
9
Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.二氢叶酸还原酶活性增加作为白血病耐药的可能基础。
Nature. 1961 Jan 7;189:39-42. doi: 10.1038/189039a0.
10
Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.培养的哺乳动物细胞中叶酸还原酶与氨甲蝶呤抗性的关系。
J Biol Chem. 1961 Mar;236:952-8.
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