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用于调强放射治疗计划验证的二维电离室阵列

Two-dimensional ionization chamber arrays for IMRT plan verification.

作者信息

Poppe Bjoern, Blechschmidt Arne, Djouguela Armand, Kollhoff Ralf, Rubach Antje, Willborn Kay C, Harder Dietrich

机构信息

Klinik fuer Strahlentherapie und Internistische Onkologie, Pius-Hospital, Oldenburg, Germany.

出版信息

Med Phys. 2006 Apr;33(4):1005-15. doi: 10.1118/1.2179167.

Abstract

In this paper we describe a concept for dosimetric treatment plan verification using two-dimensional ionization chamber arrays. Two different versions of the 2D-ARRAY (PTW-Freiburg, Germany) will be presented, a matrix of 16 x 16 chambers (chamber cross section 8 mm x 8 mm; the distance between chamber centers, 16 mm) and a matrix of 27 x 27 chambers (chamber cross section 5 mm x 5 mm; the distance between chamber centers is 10 mm). The two-dimensional response function of a single chamber is experimentally determined by scanning it with a slit beam. For dosimetric plan verification, the expected two-dimensional distribution of the array signals is calculated via convolution of the planned dose distribution, obtained from the treatment planning system, with the two-dimensional response function of a single chamber. By comparing the measured two-dimensional distribution of the array signals with the expected one, a distribution of deviations is obtained that can be subjected to verification criteria, such as the gamma index criterion. As an example, this verification method is discussed for one sequence of an IMRT plan. The error detection capability is demonstrated in a case study. Both versions of two-dimensional ionization chamber arrays, together with the developed treatment plan verification strategy, have been found to provide a suitable and easy-to-handle quality assurance instrument for IMRT.

摘要

在本文中,我们描述了一种使用二维电离室阵列进行剂量治疗计划验证的概念。将展示两种不同版本的2D - ARRAY(德国弗莱堡PTW公司),一种是16×16个电离室的矩阵(电离室横截面为8 mm×8 mm;电离室中心间距为16 mm),另一种是27×27个电离室的矩阵(电离室横截面为5 mm×5 mm;电离室中心间距为10 mm)。单个电离室的二维响应函数通过用狭缝束扫描来实验确定。对于剂量计划验证,通过将从治疗计划系统获得的计划剂量分布与单个电离室的二维响应函数进行卷积,计算阵列信号的预期二维分布。通过将测量的阵列信号二维分布与预期分布进行比较,可得到偏差分布,该分布可用于验证标准,如伽马指数标准。作为示例,针对一个调强放射治疗(IMRT)计划的序列讨论了这种验证方法。在一个案例研究中展示了误差检测能力。已发现这两种版本的二维电离室阵列以及所开发的治疗计划验证策略,为IMRT提供了一种合适且易于操作的质量保证工具。

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