Watson Todd D, Azizian Allen, Squires Nancy K
Department of Psychology, Stony Brook University, Stony Brook, NY 11794-2500, USA.
Brain Res. 2006 May 30;1092(1):138-51. doi: 10.1016/j.brainres.2006.03.098. Epub 2006 May 11.
Event-related potentials (ERPs) were recorded in healthy adult participants during the performance of a modified version of the Wisconsin Card Sorting Test that was designed to isolate the effects of extradimensional (ED) and intradimensional (ID) set-shifts. ERP averages were created for ED- and ID-Shift trials, as well as for the 5th trial in each block (Maintain-Rule). Differences in sensory and longer latency ERP components were found between the ED- and ID conditions, and between the two shift conditions and the Maintain-Rule trials. Consistent with the previous literature, these data indicated that ED- and ID-Shifts require different levels of neural resources. A secondary goal of this experiment was to use the excellent temporal resolution of ERPs to examine the neural correlates of various other aspects of the performance of a set-shift task, including differences between correct shifts and the commission of errors, and the differences between the reception of correct and error feedback. Comparisons were made between ERP averages to correct ED-Shift trials and ED-Error trials, and to feedback following a correct ED-Shift compared to feedback following an error. As expected, ERP differences were found between correct trials and error trials, and between the ERP correlates of receiving different types of feedback. Overall, these data further indicate the utility of using ERP methodology to study various aspects of complex neuropsychological paradigms.
在健康成年参与者执行威斯康星卡片分类测试的修改版本时记录事件相关电位（ERP），该测试旨在分离维度外（ED）和维度内（ID）集合转换的影响。针对ED转换和ID转换试验以及每个区块的第5次试验（维持规则）创建ERP平均值。在ED和ID条件之间，以及在两种转换条件与维持规则试验之间，发现了感觉和较长潜伏期ERP成分的差异。与先前的文献一致，这些数据表明ED转换和ID转换需要不同水平的神经资源。本实验的第二个目标是利用ERP出色的时间分辨率来检查集合转换任务执行的其他各个方面的神经相关性，包括正确转换与错误发生之间的差异，以及正确反馈与错误反馈接收之间的差异。对正确ED转换试验和ED错误试验的ERP平均值进行了比较，以及对正确ED转换后的反馈与错误后的反馈进行了比较。正如预期的那样，在正确试验和错误试验之间以及接收不同类型反馈的ERP相关性之间发现了ERP差异。总体而言，这些数据进一步表明了使用ERP方法研究复杂神经心理学范式各个方面的效用。
