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欧洲临床营养和代谢学会(ESPEN)肠内营养指南:重症监护

ESPEN Guidelines on Enteral Nutrition: Intensive care.

作者信息

Kreymann K G, Berger M M, Deutz N E P, Hiesmayr M, Jolliet P, Kazandjiev G, Nitenberg G, van den Berghe G, Wernerman J, Ebner C, Hartl W, Heymann C, Spies C

机构信息

Department of Intensive Care Medicine, University Hospital Eppendorf, Hamburg, Germany.

出版信息

Clin Nutr. 2006 Apr;25(2):210-23. doi: 10.1016/j.clnu.2006.01.021. Epub 2006 May 11.

Abstract

Enteral nutrition (EN) via tube feeding is, today, the preferred way of feeding the critically ill patient and an important means of counteracting for the catabolic state induced by severe diseases. These guidelines are intended to give evidence-based recommendations for the use of EN in patients who have a complicated course during their ICU stay, focusing particularly on those who develop a severe inflammatory response, i.e. patients who have failure of at least one organ during their ICU stay. These guidelines were developed by an interdisciplinary expert group in accordance with officially accepted standards and are based on all relevant publications since 1985. They were discussed and accepted in a consensus conference. EN should be given to all ICU patients who are not expected to be taking a full oral diet within three days. It should have begun during the first 24h using a standard high-protein formula. During the acute and initial phases of critical illness an exogenous energy supply in excess of 20-25 kcal/kg BW/day should be avoided, whereas, during recovery, the aim should be to provide values of 25-30 total kcal/kg BW/day. Supplementary parenteral nutrition remains a reserve tool and should be given only to those patients who do not reach their target nutrient intake on EN alone. There is no general indication for immune-modulating formulae in patients with severe illness or sepsis and an APACHE II Score >15. Glutamine should be supplemented in patients suffering from burns or trauma.

摘要

如今,通过管饲进行肠内营养(EN)是重症患者首选的喂养方式,也是对抗严重疾病所致分解代谢状态的重要手段。本指南旨在为入住重症监护病房(ICU)期间病情复杂的患者使用EN提供循证建议,尤其关注那些发生严重炎症反应的患者,即入住ICU期间至少有一个器官功能衰竭的患者。本指南由一个跨学科专家组按照官方认可的标准制定,基于1985年以来的所有相关出版物。它们在一次共识会议上进行了讨论并获得通过。所有预计在三天内无法完全经口进食的ICU患者均应给予EN。应在最初24小时内开始使用标准高蛋白配方。在危重病的急性期和初始阶段,应避免外源能量供应超过20 - 25千卡/千克体重/天,而在恢复期间,目标应是提供25 - 30千卡/千克体重/天的总能量值。补充性肠外营养仍是一种备用手段,仅应给予那些仅通过EN无法达到目标营养摄入量的患者。对于病情严重或患有脓毒症且急性生理学与慢性健康状况评分系统(APACHE II)评分>15的患者,没有普遍适用的免疫调节配方指征。烧伤或创伤患者应补充谷氨酰胺。

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