Bradley D J, Warhurst D C, Blaze M, Smith V
PHLS Malaria Reference Laboratory, London School of Hygiene and Tropical Medicine.
CDR (Lond Engl Rev). 1991 Apr 26;1(5):R45-8.
Imported malaria cases reported to the Malaria Reference Laboratory as occurring in the United Kingdom have remained at around 2,000 cases annually for the past seven years. However, there has been a steady increase in falciparum malaria which now accounts for 52% of the cases, with mixed infections that include P. falciparum providing another 2% of the 4083 cases reported in the two years 1989-90. Compared with 1986, there has been a substantial increase in P. falciparum of African origin and a fall in Asian P. vivax. Eight people died. Except for one case who had had a previous splenectomy, either the fatal cases had taken no prophylaxis or diagnosis was very late, usually on a mistaken assumption that the patient had influenza. The future is likely to see continuing preponderance of P. falciparum infections, with an increasing problem of multiple drug resistance.
向疟疾参考实验室报告的发生在英国的输入性疟疾病例在过去七年中一直保持在每年约2000例。然而，恶性疟原虫疟疾呈稳步上升趋势，目前占病例总数的52%，1989 - 1990年这两年报告的4083例病例中，包括恶性疟原虫的混合感染病例占另外2%。与1986年相比，非洲起源的恶性疟原虫大幅增加，而亚洲间日疟原虫减少。有8人死亡。除1例曾行脾切除术外，致命病例要么未采取预防措施，要么诊断非常晚，通常是错误地认为患者患的是流感。未来可能会继续以恶性疟原虫感染为主，多重耐药问题也会日益严重。
