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PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
J Neurooncol. 2005 Feb;71(3):215-22. doi: 10.1007/s11060-004-1718-y.
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FK228 augmented temozolomide sensitivity in human glioma cells by blocking PI3K/AKT/mTOR signal pathways.
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A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.
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TORgeting oncogene addiction for cancer therapy.
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Exploiting the PI3K/AKT pathway for cancer drug discovery.
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Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.
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The Akt-mTOR tango and its relevance to cancer.
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Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
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hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.
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Tyrosine kinases as targets for cancer therapy.
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CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
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An expanding role for mTOR in cancer.
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