Jauréguy F, Ioos V, Marzouk P, Hornstein M, Picard B, Gutierrez M C, Valeyre D
Service de Bactériologie-Virologie-Hygiène, CHU Avicenne, 125 rue de Stalingrad, 93009 Bobigny Cedex, France.
J Infect. 2007 Jan;54(1):e33-5. doi: 10.1016/j.jinf.2006.03.026. Epub 2006 May 12.
Mycobacterium heckeshornense was responsible for a severe, recurrent and chronic pulmonary infection in an immunocompetent 65-year-old woman. The pathogen, initially identified as Mycobacterium xenopi and considered as a contaminant, led to a delayed adapted antimicrobial treatment. Although M. heckeshornense is phenotypically closely related to M. xenopi, its pathogenicity is noticeably higher. Accurate molecular diagnosis methods and treatment guidelines are needed to improve the management of patients infected by this uncommon pathogen.
赫克霍恩分枝杆菌导致一名免疫功能正常的65岁女性发生严重、复发性慢性肺部感染。该病原体最初被鉴定为偶发分枝杆菌并被视为污染物,导致抗菌治疗延迟。尽管赫克霍恩分枝杆菌在表型上与偶发分枝杆菌密切相关,但其致病性明显更高。需要准确的分子诊断方法和治疗指南来改善对这种罕见病原体感染患者的管理。