Soulsby Clare T, Khela Mandeep, Yazaki Etsuro, Evans David F, Hennessy Enid, Powell-Tuck Jeremy
Centre for Adult and Paediatric Gastroenterology, Institute for Cell and Molecular Science, Barts and The London Medical School, London, UK.
Clin Nutr. 2006 Aug;25(4):671-80. doi: 10.1016/j.clnu.2005.11.015. Epub 2006 May 15.
BACKGROUND & AIMS: Continuous nasogastric infusion is commonly used to deliver enteral feed but current methods used to assess tolerance based on aspiration and measurement of gastric residual volume have been criticised. Electric impedance tomography (EIT) measures gastric emptying by monitoring changes in epigastric impedance when a meal progressively empties from the stomach.
(1) to establish whether EIT was a valid method for measuring gastric emptying during continuous nasogastric infusion by comparing it with gamma scintigraphy (GS) and (2) to provide data on gastric emptying patterns during continuous nasogastric infusion.
Gastric emptying of 400 ml of enteral feed given over 200 min was measured simultaneously using EIT and GS in 10 healthy volunteers (five male and five female).
Gastric emptying curves were obtained in 10 subjects by EIT but only eight by GS. Visual examination of the curves showed reasonable agreement. Patterns of emptying and filling during continuous nasogastric infusion were variable between individuals; the prevailing pattern was a trend towards a steady-state volume of approximately 50-125 ml.
While EIT does not provide an accurate estimate of gastric volume during continuous infusion, it does show patterns of gastric emptying over time. With further development this could make it a useful tool for monitoring gastric emptying in patients at risk of gastroparesis.
持续鼻胃管输注常用于肠内营养供给，但目前基于抽吸和测量胃残余量来评估耐受性的方法受到了批评。电阻抗断层扫描（EIT）通过监测进餐时胃内食物逐渐排空过程中上腹部阻抗的变化来测量胃排空。
（1）通过与γ闪烁扫描法（GS）比较，确定EIT是否是连续鼻胃管输注期间测量胃排空的有效方法；（2）提供连续鼻胃管输注期间胃排空模式的数据。
在10名健康志愿者（5名男性和5名女性）中，同时使用EIT和GS测量200分钟内输注400毫升肠内营养时的胃排空情况。
10名受试者通过EIT获得了胃排空曲线，而通过GS仅获得了8名受试者的胃排空曲线。曲线的视觉检查显示有合理的一致性。连续鼻胃管输注期间的排空和充盈模式在个体之间存在差异；主要模式是趋向于达到约50 - 125毫升的稳定体积。
虽然EIT在持续输注期间不能准确估计胃容量，但它确实显示了胃排空随时间的模式。随着进一步发展，这可能使其成为监测胃轻瘫风险患者胃排空的有用工具。
