Fatal exacerbation of fibrosing alveolitis associated with systemic sclerosis in a patient treated with adalimumab.
作者信息
Allanore Y, Devos-François G, Caramella C, Boumier P, Jounieaux V, Kahan A
出版信息
Ann Rheum Dis. 2006 Jun;65(6):834-5. doi: 10.1136/ard.2005.044453.
Abstract
摘要
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Fatal exacerbation of rheumatoid arthritis associated fibrosing alveolitis in patients given infliximab.使用英夫利昔单抗的类风湿关节炎相关纤维化肺泡炎患者出现致命性病情加重。
BMJ. 2004 Nov 27;329(7477):1266. doi: 10.1136/bmj.329.7477.1266.
2
Antagonistic effects of TNF-alpha on TGF-beta signaling through down-regulation of TGF-beta receptor type II in human dermal fibroblasts.肿瘤坏死因子-α通过下调人皮肤成纤维细胞中Ⅱ型转化生长因子-β受体对转化生长因子-β信号传导的拮抗作用。
J Immunol. 2003 Oct 1;171(7):3855-62. doi: 10.4049/jimmunol.171.7.3855.
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Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha.系统性硬化症 Th2 细胞通过膜相关肿瘤坏死因子α抑制真皮成纤维细胞的胶原蛋白生成。
Arthritis Rheum. 2003 Sep;48(9):2593-604. doi: 10.1002/art.11129.
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Elevated expression of the genes encoding TNF-alpha and thromboxane synthase in leucocytes from patients with systemic sclerosis.系统性硬化症患者白细胞中编码肿瘤坏死因子-α和血栓素合酶的基因表达升高。
Rheumatology (Oxford). 2002 Aug;41(8):869-75. doi: 10.1093/rheumatology/41.8.869.
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Scleroderma (systemic sclerosis): classification, subsets and pathogenesis.硬皮病（系统性硬化症）：分类、亚型及发病机制
J Rheumatol. 1988 Feb;15(2):202-5.
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