Marran Lynn F, De Land Paul N, Nguyen Andrew L
Southern California College of Optometry, Fullerton, California 92835, USA.
Optom Vis Sci. 2006 May;83(5):281-9. doi: 10.1097/01.opx.0000216097.78951.7b.
Accommodative insufficiency (AI) and convergence insufficiency (CI) have been associated with similar symptomology and frequently present at the same time. The severity of symptomology in CI has been linked to the severity of the CI, suggesting a dose-dependent relationship. However, with increasing severity of CI also comes increased comorbidity of AI. AI alone has been shown to cause significant symptomology. We hypothesize that AI drives the symptoms in CI with a comorbid AI condition (CIwAI) and that it is the increased coincidence of AI, rather than increased severity of CI, which causes additional symptomology.
Elementary school children (n = 299) participated in a vision screening that included tests for CI and AI and the CISS-V15 symptom survey. They were categorized into four groups:1) normal binocular vision (NBV); 2) AI-only; 3) CI-only; and 4) CIwAI. One hundred seventy elementary school children fell into the categories of interest.
Pairwise comparison of the group means on the symptom survey showed: 1) children with AI-only (mean = 19.7, p = 0.006) and children with CIwAI (mean = 22.8, p = 0.001) had significantly higher symptom scores than children with NBV (mean = 10.3); and 2) children with CI-only (mean = 12.9, p = 0.54) had a similar symptom score to children with NBV. Using a two-factor analysis of variance (AI and CI), the AI effect was significant (AI mean = 21.56; no AI mean = 11.56, p < 0.001), whereas neither the CI effect (p = 0.16) nor the CI by AI interaction effect (p = 0.66) were significant.
CI is a separate and unique clinical condition and can occur without a comorbid AI condition, our CI-only group. Past reports of high symptom scores for children with CI are the result of the presence of AI, a common comorbid condition. When AI is factored out, and children with CI only are evaluated, they are not significantly more symptomatic than children with NBV.
调节不足(AI)和集合不足(CI)具有相似的症状表现,且常同时出现。CI症状的严重程度与CI的严重程度相关,提示存在剂量依赖关系。然而,随着CI严重程度的增加,AI的合并症也增多。单独的AI已被证明会导致明显的症状。我们假设,在合并AI的CI(CIwAI)情况下,AI会引发CI的症状,并且是AI发生率的增加,而非CI严重程度的增加,导致了额外的症状。
小学生(n = 299)参与了一项视力筛查,其中包括CI和AI测试以及CISS-V15症状调查。他们被分为四组:1)双眼视力正常(NBV);2)仅AI;3)仅CI;4)CIwAI。170名小学生属于感兴趣的类别。
症状调查中各组均值的两两比较显示:1)仅AI的儿童(均值 = 19.7,p = 0.006)和CIwAI的儿童(均值 = 22.8,p = 0.001)的症状评分显著高于NBV儿童(均值 = 10.3);2)仅CI的儿童(均值 = 12.9,p = 0.54)与NBV儿童的症状评分相似。使用双因素方差分析(AI和CI),AI效应显著(AI均值 = 21.56;无AI均值 = 11.56,p < 0.001),而CI效应(p = 0.16)和AI与CI的交互效应(p = 0.66)均不显著。
CI是一种独立且独特的临床病症,可在无合并AI病症(即我们的仅CI组)的情况下发生。过去关于CI儿童症状评分高的报道是由于存在AI这一常见合并症。当排除AI因素,仅对CI儿童进行评估时,他们的症状并不比NBV儿童更显著。