Razzak A H, Wais S A, Saeid A Y
Department of Pathology, College of Medicine, University of Duhok, Iraq.
East Mediterr Health J. 2005 Jul;11(4):625-32.
To identify the true contribution of toxoplasmosis to fetal loss and bad obstetric history, we tested 310 women, 77.4% of whom had had single or multiple fetal loss, for evidence of infection. The study was conducted in Duhok, northern Iraq, from July 2002 till September 2003. All the women were examined for the presence of toxoplasma-specific IgM antibodies by enzyme-linked immunofluorescent assay; only 3 (0.97%) tested positive. We also tested 187 of the women by latex agglutination test; 55 tested positive. Histopathological examination was done for 9 pregnant women who tested positive by the latex agglutination test but we found no evidence of toxoplasma infection. The results indicate that the contribution of toxoplasmosis to fetal loss in our region is greatly overestimated.
为确定弓形虫病对胎儿丢失及不良产科病史的实际影响，我们对310名女性进行了检测，其中77.4%的女性曾有过单次或多次胎儿丢失，以寻找感染证据。该研究于2002年7月至2003年9月在伊拉克北部的杜胡克进行。所有女性均通过酶联免疫荧光法检测弓形虫特异性IgM抗体；仅3人（0.97%）检测呈阳性。我们还通过乳胶凝集试验对其中187名女性进行了检测；55人检测呈阳性。对9名通过乳胶凝集试验检测呈阳性的孕妇进行了组织病理学检查，但未发现弓形虫感染的证据。结果表明，在我们地区，弓形虫病对胎儿丢失的影响被大大高估了。
